Results 61 to 70 of about 14,831,592 (247)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

High-throughput phenotyping using digital and hyperspectral imaging-derived biomarkers for genotypic nitrogen response

open access: yes, 2020
A correction has been published: Journal of Experimental Botany, Volume 72, Issue 13, 22 June 2021, Page 5093, https://doi.org/10.1093/jxb/erab126Abstract:The development of crop varieties with higher nitrogen use efficiency is crucial for sustainable ...
German Spangenberg (9477560)   +7 more
core   +2 more sources

An automatable, field camera track system for phenotyping crop lodging and crop movement

open access: yesHardwareX, 2018
High throughput phenotyping systems enable rapid data collection for plant breeders. Some plant traits such as lodging, or the breaking and falling over of plant stems under wind stress, are complex and not easily measured through existing high ...
Alexander Q. Susko   +4 more
doaj   +1 more source

Optimizing pollencounter for high throughput phenotyping of pollen quality in tomatoes

open access: yesMethodsX, 2020
The macro “PollenCounter” in ImageJ was initially developed to assess pollen viability in grapevine. We set out to see if PollenCounter could be used to assess pollen number and viability in tomatoes.
Mathieu Anatole Tele Ayenan   +5 more
doaj   +1 more source

High throughput phenotyping of cross-sectional morphology to assess stalk lodging resistance

open access: yesPlant Methods, 2022
Background Stalk lodging (mechanical failure of plant stems during windstorms) leads to global yield losses in cereal crops estimated to range from 5% to 25% annually.
Yusuf A. Oduntan   +2 more
doaj   +1 more source

High-throughput phenotyping using digital and hyperspectral imaging-derived biomarkers for genotypic nitrogen response

open access: yes, 2021
A correction has been published: Journal of Experimental Botany, Volume 72, Issue 13, 22 June 2021, Page 5093, https://doi.org/10.1093/jxb/erab126Abstract: The development of crop varieties with higher nitrogen use efficiency is crucial for sustainable ...
Bikram P Banerjee (11173710)   +7 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Can High Throughput Phenotyping Help Food Security in the Mediterranean Area?

open access: yesFrontiers in Plant Science, 2019
According to the IPCC 2014 report the Mediterranean region will be affected by strong climatic changes, both in terms of average temperature and of precipitations regime.
Donatella Danzi   +11 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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