Results 71 to 80 of about 62,485 (295)

Wheat rusts never sleep but neither do sequencers: will pathogenomics transform the way plant diseases are managed? [PDF]

open access: yes, 2015
Field pathogenomics adds highly informative data to surveillance surveys by enabling rapid evaluation of pathogen variability, population structure and host ...
Derevnina, Lida, Michelmore, Richard W
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

High-throughput phenotyping for trait detection in vineyards

open access: yesBIO Web of Conferences, 2015
Recently several papers appeared describing initial steps for novel phenotyping technologies in grapevine management, research and breeding. Kicherer and coworkers were the first using a robotic device which permits to follow a GPS track, stopping in the
Kicherer Anna   +2 more
doaj   +1 more source

High throughput phenotyping methods for screening rice germplasm under water limited field conditions [PDF]

open access: yes, 2010
A Cirad project (Orytage) involving NARS and IRC aims at developing an international phenotyping network for rice adaptations to drought and thermal stresses in the context of gene discovery and genetic mapping.
Audebert, Alain   +4 more
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

An automatable, field camera track system for phenotyping crop lodging and crop movement

open access: yesHardwareX, 2018
High throughput phenotyping systems enable rapid data collection for plant breeders. Some plant traits such as lodging, or the breaking and falling over of plant stems under wind stress, are complex and not easily measured through existing high ...
Alexander Q. Susko   +4 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2020 [PDF]

open access: yes, 2020
At the end of 2019, all CGIAR centers had submitted improvement plans based on an EiB template and in close collaboration with EiB staff while – in a parallel process with breeding programs, funders and private sector representatives – a vision for ...
CGIAR Excellence in Breeding Platform
core  

Internal efficiency of nutrient utilization: what is it and how to measure it during vegetative plant growth? [PDF]

open access: yes, 2015
Efficient use of the resources required by plants to sustain crop production is considered an important objective in agriculture. In this context, the idea of developing crops with an enhanced ability to utilize mineral nutrients already taken up by ...
Moriconi, Jorge Ignacio   +2 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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