Results 91 to 100 of about 14,831,592 (247)
Advanced Healthcare Materials, EarlyView.Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park +5 more
wiley +1 more source
High-throughput automated olfactory phenotyping of group-housed mice.
, 2020 Behavioral phenotyping of mice is often compromised by manual interventions of the experimenter and limited throughput. Here, we describe a fully automated behavior setup that allows for quantitative analysis of mouse olfaction with minimized ...
Andreas T Schaefer (8119094) +2 more
core
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Advanced Materials, EarlyView.A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte +21 more
wiley +1 more source
Preliminary high-throughput phenotyping analysis in grapevines under drought
BIO Web of Conferences, 2019 This study reports correlative information between leaf water potential (ψ), total leaf area of draughted grapevines (Vitis vinifera L.) and non-destructive image analysis techniques.
Briglia Nunzio +5 more
doaj +1 more source
Advanced Materials, EarlyView.An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi +5 more
wiley +1 more source
High‐Throughput Field Phenotyping to Assess Irrigation Treatment Effects in Quinoa
Agrosystems, Geosciences & Environment, 2019 Core Ideas Water stress in multiple quinoa varieties were introduced. Remote sensing technologies were evaluated to assess water stress response. Handheld and unmanned aerial system based sensors provided reliable data. Thermal imaging data could capture
Sindhuja Sankaran +4 more
doaj +1 more source
Advanced Materials, EarlyView.Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source
Developing Growth‐Associated Molecular Markers Via High‐Throughput Phenotyping in Spinach
The Plant Genome, 2019 Core Ideas High‐throughput imaging and genomic information can be combined to optimize marker development. Genome‐wide association studies identified loci associated with plant growth traits. We identified candidate genes associated with plant growth and
Henry O. Awika +7 more
doaj +1 more source
Iterative Selection of DNA Nanostructures for Cellular Uptake
Advanced Materials, EarlyView.DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar +4 more
wiley +1 more source