Results 91 to 100 of about 615,917 (326)
Traditional plant breeding evaluation methods are time-consuming, labor-intensive, and costly. Accurate and rapid phenotypic trait data acquisition and analysis can improve genomic selection and accelerate cultivar development.
Y. Ampatzidis, Victor Partel
semanticscholar +1 more source
A two-stage approach for the spatio-temporal analysis of high-throughput phenotyping data
High throughput phenotyping (HTP) platforms and devices are increasingly used for the characterization of growth and developmental processes for large sets of plant genotypes.
Diana M. Pérez-Valencia +7 more
semanticscholar +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Professor: A motorized field-based phenotyping cart
An easy-to-customize, low-cost, low disturbance, motorized, and adjustable proximal sensing cart for field-based high-throughput phenotyping is described. General dimensions, motor specifications, and a remote operation application are given.
Alison L. Thompson +7 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A Review of Imaging Techniques for Plant Phenotyping
Given the rapid development of plant genomic technologies, a lack of access to plant phenotyping capabilities limits our ability to dissect the genetics of quantitative traits. Effective, high-throughput phenotyping platforms have recently been developed
Lei Li, Qin Zhang, Danfeng Huang
doaj +1 more source
TERMINOLOGICAL MAPPING FOR HIGH THROUGHPUT COMPARATIVE BIOLOGY OF PHENOTYPES [PDF]
Comparative biological studies have led to remarkable biomedical discoveries. While genomic science and technologies are advancing rapidly, our ability to precisely specify a phenotype and compare it to related phenotypes of other organisms remains challenging.
Yves A. Lussier, Jianrong Li
openaire +3 more sources
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
High-throughput phenotyping for trait detection in vineyards
Recently several papers appeared describing initial steps for novel phenotyping technologies in grapevine management, research and breeding. Kicherer and coworkers were the first using a robotic device which permits to follow a GPS track, stopping in the
Kicherer Anna +2 more
doaj +1 more source

