Results 181 to 190 of about 1,236,846 (314)

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

Advanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy, Chuan‐En Lu, Kai Liu, Audrey Gallud   +3 more
wiley   +1 more source

BARCODE: high throughput screening and analysis of soft active materials. [PDF]

Nat Commun
Chen Q, Sriram A, Das A, Matic K, Hendija M, Tonry K, Ross JL, Das M, McGorty RJ, Robertson-Anderson RM, Valentine MT.   +10 more
europepmc   +1 more source

Scalable Thermal Engineering via Femtosecond Laser‐Direct‐Written Phononic Nanostructures

Advanced Functional Materials, EarlyView.
This study demonstrates that femtosecond laser‐induced periodic surface structures (fs‐LIPSS) can function as phononic metasurfaces, reducing thermal conductivity below the plain thin‐film limit. Phonon Monte Carlo analysis reveals that the periodic structures restrict phonon mean free paths.
Hiroki Hamma, Roman Anufriev, Kazuyoshi Fushinobu, Masahiro Nomura, Byunggi Kim   +4 more
wiley   +1 more source

Large row-constrained supersaturated designs for high-throughput screening. [PDF]

Biometrics
Smucker BJ, Wright SE, Williams I, Page RC, Kiss AJ, Silwal SB, Weese M, Edwards DJ.   +7 more
europepmc   +1 more source

Universal Electronic‐Structure Relationship Governing Intrinsic Magnetic Properties in Permanent Magnets

Advanced Functional Materials, EarlyView.
Permanent magnets derive their extraordinary strength from deep, universal electronic‐structure principles that control magnetization, anisotropy, and intrinsic performance. This work uncovers those governing rules, examines modern modeling and AI‐driven discovery methods, identifies critical bottlenecks, and reveals electronic fingerprints shared ...
Prashant Singh
wiley   +1 more source

Generation of high-performance human cardiomyocytes and engineered heart tissues from extended pluripotent stem cells

Cell Discovery, 2022
Li Li, Zhongjun Wan, Ruxiang Wang, Yuxin Zhao, Yida Ye, Pengcheng Yang, Yan Qi, Wei Jiang, Lin Cai, Donghui Zhang   +9 more
doaj   +1 more source

High-throughput screening of drug libraries identifies a new synergistic drug combination for the treatment of retinoblastoma. [PDF]

PLoS One
Tseng PJ, Sinenko IL, Chambon M, Banfi D, Zugbi S, Cancela MB, Glinkina KA, Turcatti G, Stathopoulos C, Schaiquevich P, Munier FL, Dyson PJ.   +11 more
europepmc   +1 more source

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

Advanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian, Talin Ebrahimian, Jonathan Miranda O'Connor, Janusz Rak, Stephanie Lehoux, Maryam Tabrizian   +5 more
wiley   +1 more source

GelDrop Array High-Throughput Screening in Nematodes. [PDF]

MicroPubl Biol
Wan X, Sternberg PW.
europepmc   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source