Results 161 to 170 of about 19,076,274 (291)

High-Throughput Screening of Cyanobacterial PHB Production Using Fluorescence-Based Detection. [PDF]

Microb Biotechnol
Julià AL, Altamira-Algarra B, Garcia J, Gonzalez-Flo E.   +3 more
europepmc   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

High-throughput Screening of Sequence Elements Associated with RNA Localization. [PDF]

Comput Struct Biotechnol J
Zeng X, Lin Y, Cai M, Lin J, Zhang Y, Yao M, Zhou J.   +6 more
europepmc   +1 more source

Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms

Advanced Healthcare Materials, EarlyView.
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet, Charles Handschin, Theo Desigaux, Nathalie Dusserre, Marie‐Laure Stachowicz, Shane Fennell, Malou Lea, Silvia Arcucci, Benoît Thibault, Jean‐Christophe Fricain, Julie Guillermet‐Guibert, Hugo Oliveira   +11 more
wiley   +1 more source

Trylons: Polyamide Surrogate Substrates Enable High-Throughput Screening of Nylon-Degrading Enzymes. [PDF]

Chembiochem
Rangaswamy AMM, Roy FM, Cleveland ME, Keillor JW.   +3 more
europepmc   +1 more source

A 3D‐Printed Model of Human Lactation

Advanced Healthcare Materials, EarlyView.
Breastfeeding supports infant and maternal health, yet in vitro models that mimic human lactation remain scarce. Here, light‐based 3D printing creates high‐resolution, alveoli‐inspired microwells that guide breast cells into polarized microtissues. The printed scaffolds embed slow‐release prolactin microcrystals to deliver hormonal cues, enabling human
Amelia Hasenauer, Marcy Zenobi‐Wong
wiley   +1 more source

In silico high-throughput screening system for INMT activators in prostate cancer therapy. [PDF]

Front Pharmacol
Zheng H, Cao S, Kong Z, Xin P, Bi J, Wang J.   +5 more
europepmc   +1 more source

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source

SLAS special issue editorial 2025: Outcomes from antiviral drug discovery for pathogens of pandemic concern

SLAS Discovery
Timothy P. Spicer, Louis D. Scampavia
doaj   +1 more source

AS-TLC-Based High-Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor. [PDF]

Adv Sci (Weinh)
Wang M, Fu S, Xu Y, Gao J, Ren J, Yang X, Xu H, Sun G, Li Y, Wang Y, Jin L, Chen P, Xu Y, Li J, Lin H, Hu C, Chen K, Xiong H, Luo C, Chen S.   +19 more
europepmc   +1 more source