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Briefings Bioinform., 2020
Exploring protein-ligand interactions is a subject of immense interest, as it provides deeper insights into molecular recognition, mechanism of interaction and subsequent functions.
Taj Mohammad, Yash Mathur, M. Hassan
semanticscholar +1 more source
Exploring protein-ligand interactions is a subject of immense interest, as it provides deeper insights into molecular recognition, mechanism of interaction and subsequent functions.
Taj Mohammad, Yash Mathur, M. Hassan
semanticscholar +1 more source
High-Throughput Screening: today's biochemical and cell-based approaches.
Drug Discovery Today, 2020High-throughput screening (HTS) provides starting chemical matter in the adventure of developing a new drug. In this review, we survey several HTS methods used today for hit identification, organized in two main flavors: biochemical and cell-based assays.
V. Blay +3 more
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High-Throughput Screening Technology in Industrial Biotechnology.
Trends in Biotechnology, 2020Based on the development of automatic devices and rapid assay methods, various high-throughput screening (HTS) strategies have been established for improving the performance of industrial microorganisms.
Weizhu Zeng +4 more
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Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening
bioRxiv, 20202019 Novel Coronavirus (2019-nCoV) is a virus identified as the cause of the outbreak of pneumonia first detected in Wuhan, China. Investigations on the transmissibility, severity, and other features associated with this virus are ongoing.
Yan Li +8 more
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High-Throughput Crystallization Screening
2014Protein structure determination by X-ray crystallography is dependent on obtaining a single protein crystal suitable for diffraction data collection. Due to this requirement, protein crystallization represents a key step in protein structure determination.
Tatiana, Skarina +3 more
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Lab on a Chip, 2020
In two decades of development, impressive strides have been made for automating basic laboratory operations in droplet-based microfluidics, allowing the emergence of a new form of high-throughput screening and experimentation in nanoliter to femtoliter ...
E. Payne +3 more
semanticscholar +1 more source
In two decades of development, impressive strides have been made for automating basic laboratory operations in droplet-based microfluidics, allowing the emergence of a new form of high-throughput screening and experimentation in nanoliter to femtoliter ...
E. Payne +3 more
semanticscholar +1 more source
High-throughput screening: designer screens
Nature Methods, 2009Some researchers say an eighty-year-old statistical method can make setting up and analyzing high-throughput screens and large-scale experiments faster and more efficient. So why are more biologists not flocking to use this tool?
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High Throughput Screening Informatics
Combinatorial Chemistry & High Throughput Screening, 2008High throughput screening (HTS), an industrial effort to leverage developments in the areas of modern robotics, data analysis and control software, liquid handling devices, and sensitive detectors, has played a pivotal role in the drug discovery process, allowing researchers to efficiently screen millions of compounds to identify tractable small ...
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High-throughput screening for efficient microbial biotechnology.
Current Opinion in Biotechnology, 2020Microbial systems have been widely studied and exploited through genetic engineering to address industrial needs and societal challenges. However, owing to their complexity, singular approaches often do not yield desired or optimal results, pushing ...
Aditya P. Sarnaik +3 more
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High-throughput screening technologies
2003In the past 5 years the world of high-throughput screening (HTS), which targets lead discovery for both pharmaceutical and agrochemical applications, is in a highly rapid developmental stage. Today, restructuring the drug discovery programs to develop highest performance is a key issue of pharmaceutical companies.
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