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High-Throughput Crystallization Screening
2014Protein structure determination by X-ray crystallography is dependent on obtaining a single protein crystal suitable for diffraction data collection. Due to this requirement, protein crystallization represents a key step in protein structure determination.
Tatiana, Skarina +3 more
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High-throughput screening: designer screens
Nature Methods, 2009Some researchers say an eighty-year-old statistical method can make setting up and analyzing high-throughput screens and large-scale experiments faster and more efficient. So why are more biologists not flocking to use this tool?
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High Throughput Screening Informatics
Combinatorial Chemistry & High Throughput Screening, 2008High throughput screening (HTS), an industrial effort to leverage developments in the areas of modern robotics, data analysis and control software, liquid handling devices, and sensitive detectors, has played a pivotal role in the drug discovery process, allowing researchers to efficiently screen millions of compounds to identify tractable small ...
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High-throughput screening technologies
2003In the past 5 years the world of high-throughput screening (HTS), which targets lead discovery for both pharmaceutical and agrochemical applications, is in a highly rapid developmental stage. Today, restructuring the drug discovery programs to develop highest performance is a key issue of pharmaceutical companies.
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2014
Ion channels are a class of proteins that are attractive human, animal, and crop health targets. Ion channels can be considered high-gain (physiologically speaking), high-reward (therapeutic benefit) and high technology (difficult assay development) drug targets.
Alexander Böcker +2 more
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Ion channels are a class of proteins that are attractive human, animal, and crop health targets. Ion channels can be considered high-gain (physiologically speaking), high-reward (therapeutic benefit) and high technology (difficult assay development) drug targets.
Alexander Böcker +2 more
openaire +2 more sources
High throughput drug screening
Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders, 2004openaire +2 more sources