Results 121 to 130 of about 308,924 (265)

Unveiling Neonatal Pneumonia Microbiome by High-throughput Sequencing and Droplet Culturomics. [PDF]

Genomics Proteomics Bioinformatics
Wang 王则锐 Z, Cheng 程欣 X, Xu 徐义斌 Y, Wang 汪之一 Z, Ma 马立艳 L, Li 李埰明 C, Jiang 姜世泽 S, Li 黎雨尘 Y, Guo 郭水龙 S, Du 杜文斌 W.   +9 more
europepmc   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

High throughput sequencing in the diagnosis and surveillance of tick-borne diseases: A narrative review. [PDF]

One Health
Bisso YI, Duron O, Plantard O, Prevost G, Jaulhac B, Boyer P.   +5 more
europepmc   +1 more source

High Throughput Sequencing and Cancer Genetics [PDF]

Cell Cycle, 2002
openaire   +2 more sources

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Gut microbiota composition correlates with insomnia severity: insights from high-throughput sequencing analysis. [PDF]

Front Microbiol
Xu Z, Zhang J, Zhou H, Zhang L, Zhang X.
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

High-Throughput Sequencing Reveals Regional Diversification of Cucurbit-Infecting Begomoviruses in Eastern Saudi Arabia. [PDF]

Viruses
Sattar MN, Al Hashedi SA, Almaghasla MI, El-Ganainy SM, Al-Shoaibi AA, Munir M.   +5 more
europepmc   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

MicroRNAs from colostrum and mature cow milk: High-throughput sequencing and functional enrichment. [PDF]

Food Chem (Oxf)
Ali AH, Najjar Z, Liu SQ, Ayyash M.
europepmc   +1 more source