Results 131 to 140 of about 5,794,747 (285)

Evaluation of Psychiatric High and Intensive Care (EPHIC-study): monitoring innovative care from a value-based approach

open access: yesEuropean Psychiatry
Introduction Systematic monitoring and evaluation of innovative healthcare programs are essential to develop sustainable solutions to health needs in the population (Porter & Teisberg, 2006).
H. Demunter   +4 more
doaj   +1 more source

Pediatric Residents' Experiences With High-Value Care at an Academic Children's Hospital. [PDF]

open access: yesJ Grad Med Educ, 2022
Seltz LB   +4 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Imaging is Not Indicated in Staging of Asymptomatic Patients with Early Breast Cancer – Are We Following Current Recommendations?

open access: yesJournal of Scientific Innovation in Medicine, 2020
Ryan Leibrandt   +4 more
doaj   +1 more source

Analisis Pelaksanaan Promosi Kesehatan Bagi Karyawan Berisiko Tinggi Penyakit Degeneratif oleh Health Care Center PT Holcim Indonesia Tbk Cilacap Plant [PDF]

open access: yes, 2015
Based on Medical Check Up (MCU), counted by Framingham score method, held by Health Care Center, 50% employess have a high risk to be infected degenerative diseases, especially diabetes mellitus, hypertension, cardiovascular seen from the measurement of ...

core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Hubungan Pemeriksaan Antenatal Care (Anc) Dengan Kejadian Berat Badan Lahir Rendah (Bblr) Di Wilayah Kerja RSUD Tobelo [PDF]

open access: yes, 2017
Abstracs: Inspection of Antenatal Care (ANC) is an important part of antenatal care services that form of administration. Antenatal care can be used as an initial screening of the condition of the baby to be born.
Kundre, R. (Rina)   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Utilizing Kern's Six-Step Approach to Develop a Novel Curriculum for Enhancing Pediatric Resident Understanding of Health Care Costs

open access: yesMedEdPORTAL
Introduction Although cost awareness and advocacy for quality care are core GME competencies, high-value care (HVC) curricula remain limited. Growing evidence shows families increasingly want cost conversations with providers, yet many providers feel ill-
Jeremy Jones   +3 more
doaj   +1 more source

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