Results 21 to 30 of about 1,176 (264)

Experimental Modeling of Forward Recovery Characteristics of IGBT for DC Circuit Breaker

Zhongguo dianli, 2021
DC circuit breaker is the main means to clear the faults in VSC-HVDC power grid. Before action of the hybrid DC circuit breaker, the IGBT in the transfer branch is in a state of zero voltage and zero current.
Hong SHEN, Cuizhi TONG, Zhonghao DONGYE, Lei QI, Qian WANG   +4 more
doaj   +1 more source

Simulation study of integrated‐gate‐commutated‐thyristor based superconducting hybrid direct current circuit breaker

High Voltage, 2023
With the development of a distributed generation, direct current (DC) load and energy‐storage equipment, voltage‐source‐converter‐based medium‐voltage DC systems (VSC‐MVDC) have attracted more attention due to its low power consumption, high reliability,
Muhammad Junaid, Wenqing Yu, Shuzhi Cao, Xiaolong Yu, Dongsheng Yu, Weilin Zong, Jianhua Wang   +6 more
doaj   +1 more source

Analysis of SF6 contact based on QPSO-SVR

Energy Reports, 2023
In the condition evaluation of the high-voltage SF6 circuit breaker, contact resistance and mass loss have a significant impact on the arc contact. To that end, this paper proposes a method based on quantum particle swarm optimization and support vector ...
Jianwei Bai, Peijun Cong, Hui Zhang, Shixun Sun, Bowen Zhang, Yong Wang, Liang Wang   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Influence of UHV GIL access on transient recovery voltage of circuit breaker

电力工程技术, 2022
The access of ultra high voltage (UHV) gas-insulated transmission line (GIL) affects both the transient recovery voltage (TRV) amplitude and the rate of rise of TRV (RRRV) of circuit breakers,which may endanger the breaking capacity of circuit breakers ...
SUN Yi, LIU Jinghui, ZHENG Xinlei, LI Jiangtao, XU Yiqing, SHI Dajun   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Research status and prospect of fault diagnosis technology for mine high voltage circuit breaker

Meikuang Anquan
This paper introduces the basic situation of mechanical fault diagnosis technology for mining high voltage circuit breaker. According to the basic process of fault diagnosis, the current research status and main shortcomings of mechanical fault diagnosis
Ali HUI, Qi QIN, Rui LI, Xiang RONG
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source