Results 111 to 120 of about 16,322,799 (308)

Hepatocyte CBX2 Safeguards Hepatic Lipid Homeostasis by Elevating Ca2+‐CaMKK2‐AMPK Signaling to Counter MASLD

open access: yesAdvanced Science, EarlyView.
In hepatocytes, CBX2 promotes H3K4me3 enrichment at the Orai1 promoter to enhance Orai1 transcriptional activation, thereby increasing intracellular Ca2+ levels. The elevated Ca2+ activates the CaMKK2‐AMPK signaling cascade, resulting in ACC phosphorylation and downstream metabolic regulation. This cascade suppresses de novo lipogenesis (Fasn, Acc, Scd‐
Xiang Wei   +18 more
wiley   +1 more source

Additional file 1: of Asiatic acid attenuates renin-angiotensin system activation and improves vascular function in high-carbohydrate, high-fat diet fed rats

open access: yes, 2016
Energy densities in the food pellets of standard chow diet and high carbohydrate high fat (HCHF) diet.
Upa Kukongviriyapan (326447)   +6 more
core   +1 more source

KRONİK OBSTRÜKTİF AKCİĞER HASTALIĞI OLAN OLGULARDA DÜŞÜK KARBONHİDRAT/ YÜKSEK YAĞ BİLEŞİMLİ BESLENMENİN SOLUNUM FONKSİYONLARINA ETKİSİ

open access: yesCerrahpaşa Medical Journal, 2014
Background.­ The aim of the study was to evaluate the effect of low carbohydrate high fat diet in stable hypercapnic chronic obstructive pulmonary disease (COPD) patients. Design.­ Respiratory function tests were performed on 14 stable COPD patients on
Günay AYDIN TOSUN   +5 more
doaj  

Impact of larval diet on fitness outcomes of Aedes aegypti mosquitoes infected with wAlbB and wMelM

open access: yesParasites & Vectors
Background Releases of Wolbachia-infected Aedes aegypti are being used to effectively control diseases caused by arboviruses, such as dengue. A well-balanced larval diet is essential for producing Wolbachia-infected mosquitoes with optimal fitness for ...
Mohd Farihan Md Yatim   +3 more
doaj   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

POTENTIAL PRO-INFLAMMATORY EFFECTS OF HIGH-CALORIE DIETS MEASURED BY BLOOD NEUTROPHIL H2O2

open access: yesTrakia Journal of Sciences
PURPOSE: The aim of the study was to evaluate the potential pro-inflammatory effects of different high-calorie diets in a rat experimental model. METHODS: A total of 56 male Wistar rats were included in the experiment.
K. Trifonova, P. Dzhelebov
doaj   +1 more source

1H NMR-based metabolite profiling of diet-induced obesity in a mouse mode [PDF]

open access: yesBMB Reports, 2012
High-fat diets (HFD) and high-carbohydrate diets (HCD)-induced obesity through different pathways, but the metabolicdifferences between these diets are not fully understood.Therefore, we applied proton nuclear magnetic resonance (1HNMR)-based ...
Jee-youn Jung1,2,#, Il Yong Kim3,#, Yo Na Kim3,#, Jin-sup Kim1,5, Jae Hoon Shin3, Zi-hey Jang1,5, Ho-Sub Lee2, Geum-Sook Hwang1,5,* & Je Kyung Seong3,4,*
doaj  

Rational Surface Engineering Reduces Advanced Glycation End‐Product Adsorption and Improves Implant Integration

open access: yesAdvanced Science, EarlyView.
Targeted surface chemical modification prevents the accumulation of advanced glycation end products (AGEs) on implant surfaces, attenuates inflammation and fibrosis, effectively restores angiogenic activity, and improves osseointegration under diabetic conditions.
Thien Ngoc Le   +13 more
wiley   +1 more source

Change in erectile function, lower urinary tract symptoms or sexual desire with a high protein or high carbohydrate diet.

open access: yes, 2016
Change in erectile function, lower urinary tract symptoms or sexual desire with a high protein or high carbohydrate diet.
Gary A. Wittert (295062)   +8 more
core   +1 more source

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