Results 131 to 140 of about 17,221,339 (259)

Lessons for WFIRST CGI from ground-based high-contrast systems

, 2018
International audienceThe Coronagraph Instrument (CGI) for NASA's Wide Field Infrared Survey Telescope (WFIRST) will constitute a dramatic step forward for high-contrast imaging, integral field spectroscopy, and polarimetry of exoplanets and ...
Cantalloube, Faustine, Cady, Eric, Ruane, Garreth, Wang, Jason J., Julien Girard, Rhodes, Jason, D., Mamadoue N'Diaye, Tiffany Meshkat, Rob G. van Holstein, Elodie Choquet, Tyler D. Groff, Jason J. Wang, Males, Jared R., Eric Cady, Jared Males, Rhodes, Jason,, Arthur Vigan, Anne-Marie Lagrange, Macintosh, Bruce, Michael Bottom, Julien Milli, Bottom, Michael, Groff, Tyler, van Holstein, Rob G., Brian Kern, Nielsen, Eric L., Girard, Julien, Wenhao Xuan, Girard, Julien H., Jeffrey K. Chilcote, Krist, John, Chilcote, Jeffrey K., N'Diaye, Mamadou, Rhodes, Jason, Milli, Julien, Garreth Ruane, de Boer, Jozua, Kern, Brian, Millar-Blanchaer, Max, Christian Marois, Jozua de Boer, Henry Ngo, Marois, Christian, Ngo, Henry, Xuan, Wenhao, John Krist, Bailey, Vanessa P., Max Millar-Blanchaer, Meshkat, Tiffany, de Rosa, Robert J., Bruce Macintosh, Robert J. De Rosa, Chilcote, Jeffrey, Males, Jared, Olivier Guyon, Choquet, Elodie, Groff, Tyler D., Faustine Cantalloube, Jason Rhodes, Vanessa P. Bailey, Lagrange, Anne-Marie, Vigan, Arthur, Millar-Blanchaer, Maxwell A., Eric L. Nielsen, N'Diaye, Mamadoue, Guyon, Olivier   +65 more
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Phase contrast imaging with a laboratory-based microfocus X-ray source [PDF]

, 2007
This project looks at the design of an in-line X-ray phase contrast imaging system, based around the Bede Microsource®, on a suitable scale for imaging small pathological samples. The system is applied to two test objects to assess feasibility of its use
Kelly, Kathryn L, Kelly, Kathryn L.
core  

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Fabrication, defect chemistry and microstructure of Mn-doped UO2

Scientific Reports
Mn-doped UO2 is under consideration for use as an accident tolerant nuclear fuel. We detail the synthesis of Mn-doped UO2 prepared via a wet co-precipitation method, which was refined to improve the yield of incorporated Mn.
H. Smith, L. T. Townsend, R. Mohun, J. F. W. Mosselmans, K. Kvashnina, Neil C. Hyatt, C. L. Corkhill   +6 more
doaj   +1 more source

Solid-state NMR on complex biomolecules: novel methods and applications [PDF]

, 2011
Solid-state NMR (ssNMR) represents a versatile technique in providing atomic-resolution information without the need for crystals or fast molecular motion required for X-ray crystallography and solution-state NMR, respectively.
NMR Spectroscopy, Nand, D., Sub NMR Spectroscopy   +2 more
core   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source