Results 121 to 130 of about 1,237,664 (289)

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

Annals of Neurology, EarlyView.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund, Connar Stanley James Westgate, Marie‐Louise Kulas Søborg, Agneta Henriette Snoer, Rigmor Højland Jensen, Thomas Folkman Hansen, Anja Sofie Petersen   +6 more
wiley   +1 more source

Apolipoprotein A-I, A-II, and VLDL-B-100 metabolism in men

Journal of Lipid Research, 2004
The impact of a low-fat diet and a high-MUFA diet on apolipoprotein A-I (apoA-I), apoA-II, and VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was compared in 65 men randomly assigned to one of two predefined ...
Sophie Desroches, Marie-Eve Paradis, Mélanie Pérusse, W. Roodly Archer, Jean Bergeron, Patrick Couture, Nathalie Bergeron, Benoît Lamarche   +7 more
doaj  

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source

HDL efflux capacity, HDL particle size, and high-risk carotid atherosclerosis in a cohort of asymptomatic older adults: the Chicago Healthy Aging Study

Journal of Lipid Research, 2017
HDL efflux capacity and HDL particle size are associated with atherosclerotic CVD (ASCVD) events in middle-aged individuals; however, it is unclear whether these associations are present in older adults.
R.Kannan Mutharasan, C.Shad Thaxton, Jarett Berry, Martha L. Daviglus, Chun Yuan, Jie Sun, Colby Ayers, Donald M. Lloyd-Jones, John T. Wilkins   +8 more
doaj  

Modeling Interconnected Modules in Multivariate Outcomes: Evaluating the Impact of Alcohol Intake on Plasma Metabolomics [PDF]

arXiv
Alcohol consumption has been shown to influence cardiovascular mechanisms in humans, leading to observable alterations in the plasma metabolomic profile. Regression models are commonly employed to investigate these effects, treating metabolomics features as the outcomes and alcohol intake as the exposure. Given the latent dependence structure among the
arxiv  

FH-TabNet: Multi-Class Familial Hypercholesterolemia Detection via a Multi-Stage Tabular Deep Learning [PDF]

arXiv
Familial Hypercholesterolemia (FH) is a genetic disorder characterized by elevated levels of Low-Density Lipoprotein (LDL) cholesterol or its associated genes. Early-stage and accurate categorization of FH is of significance allowing for timely interventions to mitigate the risk of life-threatening conditions.
arxiv  

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, EarlyView.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Lipoprotein metabolism of pregnant women is associated with both their genetic polymorphisms and those of their newborn children1

Journal of Lipid Research, 2005
To explore whether the placenta contributes to the lipoprotein metabolism of pregnant women, we took advantage of the fact that placental proteins are encoded from the fetal genome and examined the associations between lipids of 525 pregnant women and ...
Olivier S. Descamps, Monique Bruniaux, Pierre-Francois Guilmot, René Tonglet, Francis R. Heller   +4 more
doaj  

Mandible composition and properties in two selected praying mantises (Insecta, Mantodea)

The Anatomical Record, EarlyView.
Abstract Insects process their food with their cuticle‐based mouthparts. These feeding structures reflect their diversity and can, in some cases, showcase adaptations in material composition, mechanical properties, and shape to suit their specific dietary preferences.
Malo Roze, Stanislav N. Gorb, Timo Zeimet, Wencke Krings   +3 more
wiley   +1 more source