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High-Density Lipoprotein Mimetics: Focus on Synthetic High-Density Lipoprotein
The American Journal of Cardiology, 2007Epidemiologic studies show an inverse relation between high-density lipoprotein (HDL) cholesterol levels and coronary artery disease, and proof-of-concept experimental studies suggest that HDL and its apolipoproteins, specifically apolipoprotein (apo) A-I , have atheroprotective effects.
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Plasma High-Density Lipoproteins
New England Journal of Medicine, 1978WHY all the recent excitement about highdensity lipoproteins (HDL)? Because of the strong inverse relation between plasma levels of HDL and mortality from cardiovascular disease.1,2 Increased serum...
A R, Tall, D M, Small
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High density lipoprotein structure
Frontiers in Bioscience, 2003HDL particles possess important antiatherogenic functionalities and understanding of the molecular mechanisms underlying these effects requires detailed knowledge of HDL structure. This review summarizes current understanding of HDL structure. The various HDL subclasses are compared in terms of their lipid and protein compositions.
Sissel, Lund-Katz +3 more
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Diet and high density lipoproteins
Lipids, 1981AbstractThe acute and subacute effects of different diets on serum high density lipoprotein (HDL) cholesterol concentration and/or HDL composition are described. In obese normolipemic, hypercholesterolemic (type II) and hypertriglyceridemic (type IV) patients, low HDL cholesterol values remained low during total starvation for 2 weeks. Prudent diets in
P, Oster +5 more
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High Density Lipoproteins in Cholestasis
Scandinavian Journal of Gastroenterology, 1974Blomhoff, J. P. High density lipoproteins in cholestasis. Scand. J. Gastroent. 1974, 9, 591–596.Two patients with cholestasis with increased concentration of plasma free cholesterol and phospholipi...
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Genetics of high-density lipoproteins
Current Opinion in Cardiology, 2006High-density lipoproteins have multi-factorial anti-atherosclerosis properties: they have potent anti-oxidant effects and prevent the oxidation of low-density lipoproteins; they have anti-inflammatory effects; they modulate vascular endothelial cell function and transport cholesterol back to the liver for excretion into the bile - a process called ...
Zari, Dastani +3 more
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The metabolism of high-density lipoproteins
Trends in Cardiovascular Medicine, 1994Although high-density lipoproteins (HDLs) have been shown to be the best single indicator of the risk of coronary heart disease (CHD), relatively little is known about their metabolism. Accordingly, only limited strategies are available for therapeutically raising plasma HDL levels.
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High density lipoprotein in octogenarians
Biochemical Medicine, 1983High density lipoprotein (HDL) cholesterol, total cholesterol, and total triglyceride levels were assayed in the plasma of 42 octogenarians. No differences were found in the levels of HDL cholesterol and total triglycerides when comparing subjects with and without ischemic heart disease.
D, Ron, M, Aviram, J G, Brook
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Exercise and High-Density Lipoproteins
JAMA: The Journal of the American Medical Association, 1979Ever since high-density lipoprotein (HDL)-cholesterol, as a measure of the HDLs, was found to be elevated in crosscountry skiers 1 and marathon runners, 2 investigators have debated whether this is a self-selection phenomenon, ie, skinny athletic persons naturally have higher HDL levels and are attracted to long-distance competitive sports because they
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Platelet Activation by Low Density Lipoprotein and High Density Lipoprotein
Pathophysiology of Haemostasis and Thrombosis, 2006Cardiovascular disease is the main cause of death and disability in the Western society. Lipoproteins are important in the development of cardiovascular disease since they change the properties of different cells involved in atherosclerosis and thrombosis. The interaction of platelets with lipoproteins has been under intense investigation. Particularly
Suzanne J A, Korporaal +1 more
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