This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin+11 more
wiley +1 more source
Association between Non high density lipoprotein to high density lipoprotein cholesterol ratio and bone mineral density. [PDF]
Zhou Y+8 more
europepmc +1 more source
The Interaction of Apoprotein from Porcine High-Density Lipoprotein with Dimyristoyl Phosphatidylcholine [PDF]
Helmut Häuser+3 more
openalex +1 more source
Artificial Internalizing Receptors for Targeted Degradation of Extracellular Proteins
Small organic molecules that are anchored into the lipid bilayer of a mammalian cell and have an exofacial recognition ligand can act as artificial internalizing receptors. These receptors are an efficacious tool to selectively capture and internalize cognate antibodies from the extracellular environment in a protein‐specific manner.
Ane B. Søgaard+3 more
wiley +1 more source
Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR) and sarcopenia in elderly adults. [PDF]
Lin Y, Shi X, Wu W, Chen X.
europepmc +1 more source
Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan+10 more
wiley +1 more source
Non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol is a predictor for cardiovascular mortality in patients with diabetes mellitus. [PDF]
Pan D, Chen PF, Ji SY, Chen TL, Zhang H.
europepmc +1 more source
Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang+6 more
wiley +1 more source