Results 41 to 50 of about 3,622,541 (329)

Asymptotic inference for high-dimensional data

open access: yes, 2010
In this paper, we study inference for high-dimensional data characterized by small sample sizes relative to the dimension of the data. In particular, we provide an infinite-dimensional framework to study statistical models that involve situations in ...
Kuelbs, Jim, Vidyashankar, Anand N.
core   +1 more source

Feature Selection in High Dimensional Biomedical Data Based on BF-SFLA

open access: yesFrontiers in Neuroscience, 2022
High-dimensional biomedical data contained many irrelevant or weakly correlated features, which affected the efficiency of disease diagnosis. This manuscript presented a feature selection method for high-dimensional biomedical data based on the ...
Yongqiang Dai   +3 more
doaj   +1 more source

Solving $k$-means on High-dimensional Big Data

open access: yes, 2015
In recent years, there have been major efforts to develop data stream algorithms that process inputs in one pass over the data with little memory requirement.
AK Jain   +12 more
core   +1 more source

Fast Covariance Estimation for High-dimensional Functional Data [PDF]

open access: yes, 2013
For smoothing covariance functions, we propose two fast algorithms that scale linearly with the number of observations per function. Most available methods and software cannot smooth covariance matrices of dimension $J \times J$ with $J>500$; the ...
Crainiceanu, Ciprian   +3 more
core   +3 more sources

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt   +76 more
wiley   +1 more source

Proportional Odds Models with High-dimensional Data Structure [PDF]

open access: yes, 2011
The proportional odds model (POM) is the most widely used model when the response has ordered categories. In the case of high-dimensional predictor structure the common maximum likelihood approach typically fails when all predictors are included.
Tutz, Gerhard, Zahid, Faisal Maqbool
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Classification of high dimensional data using LASSO ensembles [PDF]

open access: yes, 2017
Urda, D., Franco, L. and Jerez, J.M. (2017). Classification of high dimensional data using LASSO ensembles. Proceedings IEEE SSCI'17, Symposium Series on Computational Intelligence, Honolulu, Hawaii, U.S.A. (2017).
Franco, Leonardo   +2 more
core  

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