Results 61 to 70 of about 1,253,621 (308)

Low- and High-Dimensional Asset Prices Data

, 2018
The data files contain seven low-dimensional financial research data (in .txt format) and four high-dimensional daily stock prices data (in .csv format).
Pun, C (via Mendeley Data)
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Statistical methods for the testing and estimation of linear dependence structures on paired high-dimensional data: application to genomic data [PDF]

, 2018
This thesis provides novel methodology for statistical analysis of paired high-dimensional genomic data, with the aimto identify gene interactions specific to each group of samples as well as the gene connections that change between the two classes of ...
Mestres, Adrià Caballé
core  

Statistical analysis of high-dimensional biomedical data: a gentle introduction to analytical goals, common approaches and challenges

BMC Medicine, 2023
Background In high-dimensional data (HDD) settings, the number of variables associated with each observation is very large. Prominent examples of HDD in biomedical research include omics data with a large number of variables such as many measurements ...
Jörg Rahnenführer, Riccardo De Bin, Axel Benner, Federico Ambrogi, Lara Lusa, Anne-Laure Boulesteix, Eugenia Migliavacca, Harald Binder, Stefan Michiels, Willi Sauerbrei, Lisa McShane, for topic group “High-dimensional data” (TG9) of the STRATOS initiative   +11 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Dynamic Feature Selection for Clustering High Dimensional Data Streams

IEEE Access, 2019
Change in a data stream can occur at the concept level and at the feature level. Change at the feature level can occur if new, additional features appear in the stream or if the importance and relevance of a feature changes as the stream progresses. This
Conor Fahy, Shengxiang Yang
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Evaluation of changes in prediction modelling in biomedicine using systematic reviews

BMC Medical Research Methodology
The number of prediction models proposed in the biomedical literature has been growing year on year. In the last few years there has been an increasing attention to the changes occurring in the prediction modeling landscape.
Lara Lusa, Franziska Kappenberg, Gary S. Collins, Matthias Schmid, Willi Sauerbrei, Jörg Rahnenführer, on behalf of the Topic Group for High-dimensional data of the STRATOS initiative   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Time Series Clustering from High Dimensional Data

, 2015
Due to technological advances there is the possibility to col- lect datasets of growing size and dimension. On the other hand, standard techniques do not allow the easy management of large dimensional data and new techniques need to be considered in ...
DRAGO, CARLO, Germana Scepi, Carlo Drago, SCEPI, GERMANA   +3 more
core   +1 more source