Results 41 to 50 of about 1,216,046 (262)
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Learning to visualise high-dimensional data [PDF]
Visualisation techniques focus on reducing high dimensional data to a low dimensional surface or a cube. Similar dimensional reduction is attempted in the so-called 'self-organising maps'. A number of techniques have been developed to visualise categories learnt by these maps through and exemplified by the term sequential clustering.
Ahmad, Khurshid, Vrusias, Bogdan
openaire +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Background Although recommended for the early identification and intervention for developmental impairments, monitoring of preterm infants over several years is hampered by loss of follow-up that inevitably occurs.
Lucas Anzelin +9 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FCM classifier for high-dimensional data [PDF]
A fuzzy classifier based on the fuzzy c-means (FCM) clustering has shown a decisive generalization ability in classification. The FCM classifier uses covariance structures to represent flexible shapes of clusters. Despite its effectiveness, the intense computation of covariance matrices is an impediment for classifying a set of high-dimensional data ...
Hidetomo Ichihashi +3 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Background In high-dimensional data (HDD) settings, the number of variables associated with each observation is very large. Prominent examples of HDD in biomedical research include omics data with a large number of variables such as many measurements ...
Jörg Rahnenführer +11 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Dynamic Feature Selection for Clustering High Dimensional Data Streams
Change in a data stream can occur at the concept level and at the feature level. Change at the feature level can occur if new, additional features appear in the stream or if the importance and relevance of a feature changes as the stream progresses. This
Conor Fahy, Shengxiang Yang
doaj +1 more source

