Results 61 to 70 of about 3,606,574 (279)
Stable ant‐antlion optimiser for feature selection on high‐dimensional data
Electronics Letters, 2021 High‐dimensional data exists widely in the real world, such as gene, magnetic resonance imaging (MRI), text, web data and so on. Feature selection is an effective and powerful method that is often adopted to reduce dimensions of high‐dimensional data for
Mengmeng Li +5 more
doaj +1 more source
OUTLIER DETECTION ON HIGH DIMENSIONAL DATA USING MINIMUM VECTOR VARIANCE (MVV)
Barekeng, 2022 High-dimensional data can occur in actual cases where the variable p is larger than the number of observations n. The problem that often occurs when adding data dimensions indicates that the data points will approach an outlier.
Andi Harismahyanti A. +3 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A network approach for low dimensional signatures from high throughput data
Scientific Reports, 2022 One of the main objectives of high-throughput genomics studies is to obtain a low-dimensional set of observables—a signature—for sample classification purposes (diagnosis, prognosis, stratification).
Nico Curti +4 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
K-means clustering based filter feature selection on high dimensional data
IJAIN (International Journal of Advances in Intelligent Informatics), 2016 With hundreds or thousands of features in high dimensional data, computational workload is challenging. In classification process, features which do not contribute significantly to prediction of classes, add to the computational workload.
Dewi Pramudi Ismi +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Fast robust correlation for high-dimensional data
, 2019 The product moment covariance is a cornerstone of multivariate data analysis, from which one can derive correlations, principal components, Mahalanobis distances and many other results.
Raymaekers, Jakob, Rousseeuw, Peter J.
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source