Results 81 to 90 of about 22,051,772 (250)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

High Dynamic Range and Super-Resolution Imaging From a Single Image

open access: yesIEEE Access, 2018
This paper presents an algorithm for high dynamic range (HDR) and super-resolution (SR) imaging from a single image. First, we propose a new single image HDR imaging (HDRI) method based on the Retinex approach and exploit a recent single image SR method ...
Jae Sung Park, Jae Woong Soh, Nam Ik Cho
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Descriptive Keywords: Image Processing, Image Segmentation, Signal Processing, Biological Modeling, Tone Reproduction Operator

open access: yes, 2008
Realistic display of high dynamic range images is a difficult problem. Previous methods for high dynamic range image display suffer from halo artifacts or are computationally expensive.
Display High-dynamic, Range Images
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

High Dynamic Range Imaging Using Multiple Exposures

open access: yes, 2017
It is challenging to capture a high-dynamic range (HDR) scene using a low-dynamic range (LDR) camera. This paper presents an approach for improving the dynamic range of cameras by using multiple exposure images of same scene taken under different ...
Zhou PP(周培培)   +3 more
core  

Video-rate or high-precision: A flexible range imaging camera [PDF]

open access: yes, 2008
A range imaging camera produces an output similar to a digital photograph, but every pixel in the image contains distance information as well as intensity.
Dorrington, Adrian A.   +13 more
core   +1 more source

A High Dynamic Range Image Reconstruction Network Using Feature Pre-Alignment [PDF]

open access: yesJisuanji gongcheng
Reconstructing High Dynamic Range (HDR) images from multiple Low Dynamic Range (LDR) images with varying exposures is challenging, especially in scenarios involving camera and object motion, where motion regions often introduce artifacts, thereby ...
TAN Taizhe, GONG Zhiyuan, YANG Zhuo
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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