Results 81 to 90 of about 398,318 (257)
Current Directions in Biomedical Engineering, 2017 Laser-driven acceleration of particle beams is an emerging modality under research for biomedical applications. The spatially resolved diagnostics of laser-accelerated proton bunches is crucial for their application.
Englbrecht Franz +6 more
doaj +1 more source
177 dB Linear Dynamic Range Pixels of Interest DSLR CAOS Camera
IEEE Photonics Journal, 2019 For the first time, demonstrated is an extreme linear Dynamic Range (DR) Pixels of Interest (POI) [i.e., Coded Access Optical Sensor (CAOS)] Digital Single Lens Reflex (DSLR) camera design that engages three different types of photosensors within one ...
Nabeel A. Riza, Mohsin A. Mazhar
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Enhancement in dynamic range for dual-rotating retarder Mueller matrix polarimetry
Journal of Innovative Optical Health SciencesMueller matrix polarimetry (MMP) has been proven to be a powerful tool for characterizing the microstructural features of biological samples in biomedical research and clinical diagnostics.
Jiongying Lv +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Ghost-Free HDR Imaging in Dynamic Scenes via High–Low-Frequency Decomposition
SensorsGenerating high-quality high-dynamic-range (HDR) images in dynamic scenes remains a challenging task. Recently, Transformers have been introduced into HDR imaging and have demonstrated superior performance over traditional convolutional neural networks ...
Xiang Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source