Results 111 to 120 of about 2,805,233 (318)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Advancements in Genetic Marker Exploration for Livestock Vertebral Traits with a Focus on China
AnimalsIn livestock breeding, the number of vertebrae has gained significant attention due to its impact on carcass quality and quantity. Variations in vertebral traits have been observed across different animal species and breeds, with a strong correlation to ...
Muhammad Zahoor Khan +7 more
doaj +1 more source
Coil enhancements for high efficiency wireless power transfer applications
, 2014 Achieving high efficiency with improved power transfer range and misalignment tolerance is the major design challenge in realizing Wireless Power Transfer (WPT) systems for industrial applications.
Vilathgamuwa, D. Mahinda +9 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Advances in Mechanical Engineering, 2018 A fully hydraulic variable valve system based on spark-ignition engine BJ486EQ is introduced in this article, which can provide fully variable valve lifts, valve timing, and valve opening duration.
Fei Chen +6 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Plasma-electrolyte chemical-thermal treatment of hard alloy
Next MaterialsThe possibility of using of plasma-electrolytic treatment for the hard-alloy material surface complex modification, which consists of simultaneous diffusion saturation, heat treatment and plasma-electrochemical polishing of the surface, is shown.
B.L. Krit +9 more
doaj +1 more source
Compact High Efficiency Adsorption Heat Pump
, 2012 An innovative adsorption cycle heat pump technology is presented that is compact and capable of achieving high energy efficiency for integrated space heating, air conditioning, and water heating.
Sweeney, Josh B +2 more
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