Results 141 to 150 of about 2,805,233 (318)
Efficiency Potential and Efficiency Variation in Norwegian Lower Secondary Schools [PDF]
The paper performs an efficiency analysis of the lower secondary school sector in Norway. The efficiency potential is calculated to 14 percent based on a DEA analysis with grades in core subjects (adjusted for student characteristics and family ...
Linn Renée Naper, Lars-Erik Borge
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Transcriptional regulation of SlFRIGIDA-like improve antioxidant system in tomato under cold
BMC Plant BiologyBackground Plant experience exposure to short term low temperature during early spring. In response, it activates various mechanisms to cope with the changing environment.
Maqsood Khan +9 more
doaj +1 more source
Calculated Optimal Mechanical Efficiency of a Large Capacity Reciprocating Compressor
, 2012 In this study, calculations of the mechanical efficiency of a large reciprocating compressor, developed by Mayekawa MFG. Co., Ltd., with a per cylinder suction volume of 1300 cm3 were carried out.
Anami, Keiko +4 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Polarization Independent Dynamic Beam Steering based on Liquid Crystal Integrated Metasurface
Scientific ReportsDigital Micromirror Devices, extensively employed in projection displays offer rapid, polarization-independent beam steering. However, they are constrained by microelectromechanical system limitations, resulting in reduced resolution, limited beam ...
Dian Yu +5 more
doaj +1 more source
Energy Efficiency of a Low Power Hardware Cluster for High Performance Computing
, 2017 High performance computing has become more and more limited by the hardware’s energy consumption, rendering it increasingly difficult to build even faster compute clusters, while modern low power hardware is making great improvements, regarding its ...
Zietek, Oliver +10 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source