Results 191 to 200 of about 31,917,810 (358)

High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer. [PDF]

Cell Rep Methods
Moreno AB, Ek V, Eriksson J, Sellin ME, Guy L.   +4 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Integrated broadband and high-efficiency difference frequency generation. [PDF]

Nat Commun
Li H, Guo J, Huang F, Gao H, Li H, Li H, Shi Y, Yu Z, Dai D.   +8 more
europepmc   +1 more source

Quantum dot–induced phase stabilization of α-CsPbI3 perovskite for high-efficiency photovoltaics

Science, 2016
Abhishek Swarnkar, Ashley R. Marshall, E. Sanehira, B. Chernomordik, D. Moore, Jeffrey A. Christians, T. Chakrabarti, J. Luther   +7 more
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Development of a Tool for High-Efficiency, Markerless and Iterative Genome Editing in Shouchella clausii. [PDF]

Microb Biotechnol
Cappella C, Jers C, Ninivaggi L, Bettiga M, Mijakovic I, Agrimi G, Scarcia P.   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

High efficiency, high color purity red micro-light-emitting diodes. [PDF]

Light Sci Appl
Wu Y, Xiao Y, Reddeppa M, Malhotra Y, Guo Y, Xiao J, Liu J, Wang D, Sun K, Mi Z.   +9 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Developing High-Efficiency Electroporation Protocols for Hard-To-Transform Halomonas spp. [PDF]

Microb Biotechnol
Coimbra AAB, White IJ, Rios-Solis L.
europepmc   +1 more source