Results 51 to 60 of about 1,974,678 (268)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Increasing the Wear and Corrosion Resistance of a CP-Ti Surface by Plasma Electrolytic Borocarburizing and Polishing

Surfaces
The paper examines the possibility of increasing the wear and corrosion resistance of a CP-Ti surface by duplex plasma electrolytic treatment (borocarburizing and polishing). The structure and composition of diffusion layers, their microhardness, surface
Marina A. Volosova, Sergei A. Kusmanov, Ivan V. Tambovskiy, Tatiana L. Mukhacheva, Artem P. Mitrofanov, Igor V. Suminov, Sergey N. Grigoriev   +6 more
doaj   +1 more source

Analysis of Three Channel SW Interference Adaptive Cancellation System

MATEC Web of Conferences, 2018
Aiming at the adjacent channel interference problem of short-wave, a model of three-way short-wave interference signals has been established. The interference cancellation of the short-wave interference signal of three adjacent channels is analyzed, and ...
Li Mingyang, Jiang Yunhao, Yang Jian, Liu Shiqi, Li Xing   +4 more
doaj   +1 more source

High Efficient Transformers

, 2020
Earlier conventional transformers usage in power grids has had a fairly one-sided existence for many decades. An interesting, challenging and promising solution for this is smart grids. Smart grids are more flexible ,intelligent enough to integrate a great amount of renewable energy and energy storage systems, which calls for more flexible and more ...
H.M. Maheshwarappa, Rohith Prasad, D.
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Research on Economic optimal dispatching Strategy of Microgrid based on Model Predictive Control

MATEC Web of Conferences, 2018
Because of the energy crisis caused by the shortage of fossil energy, countries begin to study low-carbon new energy and micro-grid systems related to new energy, and more importantly the energy dispatching of micro-grid is the focus of the whole micro ...
Zhang Zihan, Zhang Jie, DING Wenfang, Peng Rui, Xu Cheng   +4 more
doaj   +1 more source

Electrical Discharge Machining of Oxide Nanocomposite: Nanomodification of Surface and Subsurface Layers

Journal of Manufacturing and Materials Processing, 2020
The work is devoted to the research of the changes that occur in the subsurface layer of the workpiece during electrical discharge machining of conductive nanocomposite based on alumina with the use of a brass tool.
Sergey N. Grigoriev, Marina A. Volosova, Anna A. Okunkova, Sergey V. Fedorov, Khaled Hamdy, Pavel A. Podrabinnik, Petr M. Pivkin, Mikhail P. Kozochkin, Artur N. Porvatov   +8 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source