Results 51 to 60 of about 2,114,083 (269)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Increasing the Wear and Corrosion Resistance of a CP-Ti Surface by Plasma Electrolytic Borocarburizing and Polishing

open access: yesSurfaces
The paper examines the possibility of increasing the wear and corrosion resistance of a CP-Ti surface by duplex plasma electrolytic treatment (borocarburizing and polishing). The structure and composition of diffusion layers, their microhardness, surface
Marina A. Volosova   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analysis of Three Channel SW Interference Adaptive Cancellation System

open access: yesMATEC Web of Conferences, 2018
Aiming at the adjacent channel interference problem of short-wave, a model of three-way short-wave interference signals has been established. The interference cancellation of the short-wave interference signal of three adjacent channels is analyzed, and ...
Li Mingyang   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Optimization method for low-velocity impact identification in nanocomposite using genetic algorithm

open access: yesNanotechnology Reviews
Fiber-reinforced plastic (FRP) is prone to invisible damage caused by low-velocity impact (LVI) during service. The structural health monitoring system is of great significance for damage monitoring and maintenance of composite materials.
Wang Zhiyuan   +4 more
doaj   +1 more source

Quantitative stability analysis of Grid-Following inverter with Grid-Supporting control and stability enhancement method based on Multi-Voltage feedforward

open access: yesInternational Journal of Electrical Power & Energy Systems
Grid-following inverters with grid-supporting control (GFLI-GSC) can provide inertia and voltage support to the grid, but GSC degrades their stability under weak grid.
Song Zhang   +5 more
doaj   +1 more source

Research on Economic optimal dispatching Strategy of Microgrid based on Model Predictive Control

open access: yesMATEC Web of Conferences, 2018
Because of the energy crisis caused by the shortage of fossil energy, countries begin to study low-carbon new energy and micro-grid systems related to new energy, and more importantly the energy dispatching of micro-grid is the focus of the whole micro ...
Zhang Zihan   +4 more
doaj   +1 more source

Electrical Discharge Machining of Oxide Nanocomposite: Nanomodification of Surface and Subsurface Layers

open access: yesJournal of Manufacturing and Materials Processing, 2020
The work is devoted to the research of the changes that occur in the subsurface layer of the workpiece during electrical discharge machining of conductive nanocomposite based on alumina with the use of a brass tool.
Sergey N. Grigoriev   +8 more
doaj   +1 more source

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