Results 51 to 60 of about 2,235,408 (269)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

High Energy-Efficiency Buildings

, 2003
In cold, central European climates, hyper-insulated, heat-conserving buildings have proven a very effective way to reduce current energy consumption to 1/10 th of a traditional house. Using dry, stratified building techniques (Str/En) allows to obtain quite easily the required thermal and acoustical performances, also enhancing the construction process
IMPERADORI, MARCO, M. Lemma, MASERA, GABRIELE, ZAMBELLI, ETTORE   +3 more
openaire   +2 more sources

Electrical Discharge Machining of Oxide Nanocomposite: Nanomodification of Surface and Subsurface Layers

Journal of Manufacturing and Materials Processing, 2020
The work is devoted to the research of the changes that occur in the subsurface layer of the workpiece during electrical discharge machining of conductive nanocomposite based on alumina with the use of a brass tool.
Sergey N. Grigoriev, Marina A. Volosova, Anna A. Okunkova, Sergey V. Fedorov, Khaled Hamdy, Pavel A. Podrabinnik, Petr M. Pivkin, Mikhail P. Kozochkin, Artur N. Porvatov   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Increasing the Wear and Corrosion Resistance of a CP-Ti Surface by Plasma Electrolytic Borocarburizing and Polishing

Surfaces
The paper examines the possibility of increasing the wear and corrosion resistance of a CP-Ti surface by duplex plasma electrolytic treatment (borocarburizing and polishing). The structure and composition of diffusion layers, their microhardness, surface
Marina A. Volosova, Sergei A. Kusmanov, Ivan V. Tambovskiy, Tatiana L. Mukhacheva, Artem P. Mitrofanov, Igor V. Suminov, Sergey N. Grigoriev   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Analysis of Three Channel SW Interference Adaptive Cancellation System

MATEC Web of Conferences, 2018
Aiming at the adjacent channel interference problem of short-wave, a model of three-way short-wave interference signals has been established. The interference cancellation of the short-wave interference signal of three adjacent channels is analyzed, and ...
Li Mingyang, Jiang Yunhao, Yang Jian, Liu Shiqi, Li Xing   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Optimization method for low-velocity impact identification in nanocomposite using genetic algorithm

Nanotechnology Reviews
Fiber-reinforced plastic (FRP) is prone to invisible damage caused by low-velocity impact (LVI) during service. The structural health monitoring system is of great significance for damage monitoring and maintenance of composite materials.
Wang Zhiyuan, Chen Long, Zhu Chenyang, Liu Zhanqiang, Song Qinghua   +4 more
doaj   +1 more source

Identification method of all-operating-point admittance model for wind farms considering frequency-coupling characteristics

International Journal of Electrical Power & Energy Systems
Admittance identification is an effective tool to solve the issue of black-box admittance modeling in wind farms. However, due to the large operating range of wind farms, it is difficult to accurately identify the admittance model of wind farms under all
Zilin Zhang, Wenhua Wu, Zhiwei Xie, Yandong Chen, Yuancan Xu, Shixiang Cao, Zhihao Dai   +6 more
doaj   +1 more source