Results 21 to 30 of about 935,964 (287)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Energy calibration of the NEXT-White detector with 1% resolution near Q ββ of 136Xe [PDF]

, 2019
Excellent energy resolution is one of the primary advantages of electroluminescent high-pressure xenon TPCs. These detectors are promising tools in searching for rare physics events, such as neutrinoless double-beta decay (ββ0ν), which require precise ...
Adams, C., Arazi, L., Arnquist, I.J., Azevedo, C.D.R., Bailey, K., Ballester, F., Benlloch-Rodríguez, J.M., Borges, F.I.G.M., Byrnes, N., Carrión, J.V., Cebrián, S., Church, E., Conde, C.A.N., Contreras, T., Cárcel, S., Diesburg, M., dos Santos, J.M.F., Díaz López, G., Díaz, J., Escada, J., Esteve, R., Felkai, R., Fernandes, A.F.M., Fernandes, L.M.P., Ferrario, P., Ferreira, A.L., Freitas, E.D.C., Generowicz, J., Ghosh, S., Goldschmidt, A., González-Díaz, D., Guenette, R., Gutiérrez, R.M., Gómez-Cadenas, J.J., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C.A.O., Hernando Morata, J.A., Herrero, P., Herrero, V., Ifergan, Y., Johnston, S., Jones, B.J.P., Kekic, M., Labarga, L., Laing, A., Lebrun, P., Losada, M., López-March, N., Mano, R.D.P., Martín-Albo, J., Martínez, A., Martínez-Lema, G., McDonald, A.D., Monrabal, F., Monteiro, C.M.B., Mora, F.J., Muñoz Vidal, J., Novella, P., Nygren, D.R., Palmeiro, B., Para, A., Psihas, F., Pérez, J., Querol, M., Renner, J., Repond, J., Riordan, S., Ripoll, L., Rodríguez García, Y., Rodríguez, J., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F.P., Simón, A., Sofka, C., Sorel, M., Stiegler, T., The NEXT collaboration, Toledo, J.F., Torrent, J., Usón, A., Veloso, J.F.C.A., Webb, R., Weiss-Babai, R., White, J.T., Woodruff, K., Yahlali, N., Álvarez, V.   +90 more
core   +2 more sources

High-energy physics experiments in space

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2004
Abstract The main environmental difficulties related to HEP experimentation on satellites and balloons are described. We review ways how to face these difficulties, analyzing some paradigmatic examples of present and future experiments. Furthermore, the main features of detectors operating outside the terrestrial atmosphere are reported ...
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Grid Computing in High Energy Physics Experiments

, 2012
The High Energy Physics (HEP) [1] – often called Particle Physics – is one of the research areas where the accomplishment of scientific results is inconceivable without the infrastructure for distributed computing, the Computing Grid. The HEP is a branch of Physics that studies properties of elementary subatomic constituents of matter.
Dagmar Adamov, Pablo Saiz
openaire   +4 more sources

Performance of Calorimetry in ALICE

, 2018
The ALICE experiment at LHC studies the strong interaction sector of the Standard Model with pp, pA and AA collisions. Within the scope of the physics program, measurements of photons, neutral mesons and jets in ALICE are performed by two electromagnetic
Kharlov, Yuri
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Nuclear Track Detectors. Searches for Exotic Particles [PDF]

, 2008
We used Nuclear Track Detectors (NTD) CR39 and Makrofol for many purposes: i) Exposures at the SPS and at lower energy accelerator heavy ion beams for calibration purposes and for fragmentation studies. ii) Searches for GUT and Intermediate Mass Magnetic
A. Noll, D. Nikezic, E. Vilela, E. Witten, G. Abbiendi, G. Giacomelli, G. Giacomelli, H.L. Bradt, J. Derkaoui, L. Patrizii, M. Ambrosio, M. Ambrosio, M. Ambrosio, P.B. Price, P.B. Price, S. Balestra, S. Balestra, S. Cecchini, S. Cecchini, S. Cecchini, S. Coleman, S. Kodaira, S. Manzoor, S. Orito, S.A. Durrani, T.W. Kephart, V. Togo   +26 more
core   +2 more sources

Experiments on High-Energy Heavy-Ion Physics [PDF]

Proceedings of the 8th International Conference on Quarks and Nuclear Physics (QNP2018), 2019
High-energy heavy-ion collisions are utilized to create a new state of matter such as Quark Gluon Plasma (QGP) in various experiments at Large Hadron Collider (LHC) at CERN and Relativistic Heavy-Ion Collider (RHIC) at BNL. This new form of matter QGP is supposed to exist in early universe at high temperature and/or inside neutron stars at high density
openaire   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source