Results 91 to 100 of about 16,800,727 (310)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Cut the fat: 1% or less campaign [PDF]

open access: yes, 2001
Plan BIntroduction. Obesity is the leading contributor to the progression of chronic disease and cardiovascular disease is the number one killer of American men and women. Objective.
Schmidt, Amanda E.
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

High fat meals increases postprandial fat oxidation rate but not postprandial lipemia

open access: yesLipids in Health and Disease, 2019
Background This study investigated the effects of ingesting meals with the same calorie intake but distinct nutritional contents after exercise on postprandial lipemia the next day.
Chih-Hui Chiu   +3 more
doaj   +1 more source

HIGH FAT PERCENTAGES IN INFANT FEEDING. [PDF]

open access: yesJournal of the American Medical Association, 1908
If one may judge from the literature bearing on this subject, the attention of those most deeply interested in the artificial feeding of infants appears, at the present moment, to be largely concentrated on the digestion of the fat contained in cow's milk.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Long-term administration of DHEA prevents fat deposition in rats fed a high-fat diet

open access: yesCzech Journal of Animal Science, 2016
The effects of dehydroepiandrosterone (DHEA) on lipid metabolism and lipogenic gene mRNA expression in rats subjected to a high-fat diet were determined.
D. Chen, J. Kang, L. Li, H. Ma
doaj   +1 more source

Liver Fats and Glycogen of Hypophysectomized Rats on High Carbohydrate and High Fat Diets.

open access: yesExperimental Biology and Medicine, 1942
SummaryOn a high fat diet the glycogen content of the liver was originally lower than on a high carbohydrate diet, but it did not disappear so rapidly from the liver. Hypophysectomized rats had less liver fat and more body fat than controls on the same caloric intake of a given diet.
L. T. Samuels   +2 more
openaire   +1 more source

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