Results 51 to 60 of about 310,780 (254)
Application of high ligation in patients with varicocele
Urology Research and Practice, 2019 -
Erbil Ergenekon +2 more
doaj +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Directed assembly of DNA molecules via simultaneous ligation and digestion
BioTechniques, 2007 DNA ligation is a routine laboratory practice, yet the yield of the desired product is often very low due to competing off-pathway reactions. The sensitivity of subsequent manipulations (e.g., selection via bacterial transformation) often obviates the ...
Gregory J. Cost, Nicholas R. Cozzarelli
doaj +1 more source
FERTILITY AFETER HIGH LIGATION IN PATIENTS WITH VARICOCELE
Urology Research and Practice, 2019 -
V. SOLOK +5 more
doaj +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Stump evolution after great saphenous vein stripping with high ligation
Veins and Lymphatics, 2016 The aim of the present observational study is to show the evolution of great saphenous vein (GSV) stump in two different periods of follow up. From 2001 to 2009, 500 legs with GSV insufficiency and terminal valve reflux, operated on with stripping by ...
Paolo Casoni +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
结直肠肛门外科[Background] Whether the level of the inferior mesenteric artery ligation affects the incidence of anastomotic leakage remains unclear. [Objective] To assess the impact of the level of inferior mesenteric artery ligation on the blood flow to the ...
Qiu Xianda, Chen Zhifen
doaj +1 more source