Results 121 to 130 of about 22,385,248 (304)
Energy Efficiency on Scalable Computing Architectures
, 2011 peer reviewedNowadays, power consumption in computer systems is an active and important subject of discussion in both research and political communities.
Sierra, Daniel A. +3 more
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A Full-Cost Model for Estimating the Energy Consumption of Computing Infrastructures
, 2019 peer reviewedSince its advent in the middle of the 2000’s, the Cloud Computing (CC) paradigm is increasingly advertised as a price-effective solution to many IT problems.
Orgerie, Anne-Cecile +1 more
core +1 more source
Discover Artificial IntelligenceThe rise of Neural Language Models (NLMs) has advanced Natural Language Processing (NLP), yet their application to complex, low-resource domains like the legal field remains limited. This gap is especially pronounced for the Italian language, which lacks
Raffaele Guarasci +5 more
doaj +1 more source
High-Performance Computational Genomics.
, 2021 Next-generation sequencing data is growing at an unprecedented rate, leading to new revelations in biology, healthcare, and medicine. Many researchers use high-level programming languages to navigate and analyze this data, but as gigabytes grow to terabytes or even petabytes, high-level languages become prohibitive and impractical for performance ...
openaire +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Application of multivariate time-series model for high performance computing (HPC) fault prediction. [PDF]
PLoS One, 2023 Pei X, Yuan M, Mao G, Pang Z.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source