Results 141 to 150 of about 414,061 (317)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Performance-responsive middleware for grid computing [PDF]
The development of supportive middleware to manage resources and distributed workload across multiple administrative boundaries is of central importance to Grid computing.
Nudd, G. R. +4 more
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The Potential of High Performance Computing in Audio Engineering
High Performance Computing (HPC) resources are fast becoming more readily available. HPC hardware now exists for use in conjunction with standard desktop computers.
Wakefield, Jonathan P., Moore, David J.
core
A high performance computing technology powered multimedia fusion model in university English translation. [PDF]
PeerJ Comput Sci, 2023 Shi L, DuJiang M, Gao P.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
.Net High Performance Computing based on Windows HPC Server 2008 R2
, 2014 High performance computing is not one of the original goals for Microsoft .NET programmers, but it did bring development benefit to developers via providing a complete and robust environment for development.
Aykut, Erkin
core
Review: understanding the properties of amorphous materials with high-performance computing methods. [PDF]
Philos Trans A Math Phys Eng Sci, 2023 Christie JK.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source