Real-time pneumonia prediction using pipelined spark and high-performance computing. [PDF]
PeerJ Comput Sci, 2023 Ravikumar A, Sriraman H.
europepmc +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Retracted: Dynamic Mechanism and Decision Analysis of Urban Exhibition Tourism Development Based on High-Performance Computing. [PDF]
Comput Intell Neurosci, 2023 Intelligence And Neuroscience C.
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Leveraging Hyperspectral Data in Cognitive Environments
IEEE AccessHyperspectral Imaging (HSI) captures data across multiple wavelengths of light, including visible and non-visible spectra (e.g., infrared or ultraviolet). It is usually used to analyze the composition, structure, and condition of objects of interest in a
Massimo Micieli +5 more
doaj +1 more source
Bioinformatics and High-Performance Computing Methods for Deciphering and Fighting COVID-19-Editorial. [PDF]
BioTech (Basel), 2022 Cannataro M, Agapito G.
europepmc +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
COVID-19 Detection using adopted convolutional neural networks and high-performance computing. [PDF]
Multimed Tools Appl, 2023 Singh AK, Kumar A, Kumar V, Prakash S.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
MD-Ligand-Receptor: A High-Performance Computing Tool for Characterizing Ligand-Receptor Binding Interactions in Molecular Dynamics Trajectories. [PDF]
Int J Mol Sci, 2023 Pieroni M +6 more
europepmc +1 more source