Results 91 to 100 of about 1,123,025 (269)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Generation and control of tungsten surface dislocations during ultrasonic elliptical vibratory cutting process

Journal of Materials Research and Technology
At present, tungsten is mainly processed with geometrical accuracy as the target, and the influence law of each process parameter (PP) on tungsten surface dislocations is unclear. This limits the performance of the tungsten divertor in a high-temperature
Kaixuan Wang, Zhigang Dong, Xinming Zhang, Xiaoguang Guo, Yan Bao   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Flexible Hybrid Generator for Efficient Dual Energy Conversion from Raindrops to Electricity

Advanced Science
Electromagnetic generators are conventionally used to harvest energy from large water bodies, but they are ineffective for harvesting low hydro‐energy, such as raindrops or fogs, due to their bulky, heavy and immovable.
Yonghui Zhang, Jiahao Zhang, Huanxi Zheng, Yue Zhao, Yang Chen, Yuyang Zhou, Xiu Liu   +6 more
doaj   +1 more source

A Visual Measurement Method for Deep Holes in Composite Material Aerospace Components

Sensors
The visual measurement of deep holes in composite material workpieces constitutes a critical step in the robotic assembly of aerospace components.
Fantong Meng, Jiankun Yang, Guolin Yang, Haibo Lu, Zhigang Dong, Renke Kang, Dongming Guo, Yan Qin   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

R-AFPN: a residual asymptotic feature pyramid network for UAV aerial photography of small targets

Scientific Reports
This study proposes an improved Residual Asymptotic Feature Pyramid Network (R-AFPN) to address challenges in small target detection from the Unmanned Aerial Vehicle (UAV) perspectives, such as scale imbalance, feature extraction difficulty, occlusion ...
Zuowen Chen, Yahong Ma, Zi’an Gong, Minghao Cao, Yuyao Yang, Zhiyuan Wang, Tengjie Wang, Jing Li, Yuxi Liu   +8 more
doaj   +1 more source

Error Analysis of Normal Surface Measurements Based on Multiple Laser Displacement Sensors

Sensors
The robotic drilling of assembly holes is a crucial process in aerospace manufacturing, in which measuring the normal of the workpiece surface is a key step to guide the robot to the correct pose and guarantee the perpendicularity of the hole axis ...
Fantong Meng, Guolin Yang, Jiankun Yang, Haibo Lu, Zhigang Dong, Renke Kang, Dongming Guo, Yan Qin   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source