Results 71 to 80 of about 1,123,025 (269)

Design and Fabrication of Ultrathin Metallic Phase Shifters for Visible and Near-Infrared Wavelengths

open access: yesMicromachines
The polarization state of light is critical for biological imaging, acousto-optics, bio-navigation, and many other optical applications. Phase shifters are extensively researched for their applications in optics.
Qing Guo   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Four-dimensional reconfigurable vascular tunneling machine of spatially programmed liquid crystal elastomers

open access: yesNature Communications
Thrombosis in tortuous vessels causes blockages and pathological conditions. Current thrombolytics are inefficient, and mechanical thrombectomies lack adaptability, hindering thrombus clearance in complex geometries.
Yi Li   +20 more
doaj   +1 more source

Experiment and simulation of single diamond abrasive particle scratching RB-SiC composite material

open access: yesJin'gangshi yu moliao moju gongcheng
ObjectivesReaction-sintered silicon carbide (RB-SiC) composite materials have excellent properties such as high specific stiffness, high hardness, and corrosion resistance, and are widely used in important equipment such as space telescopes and aerospace
Dehan ZHANG   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Atomic understanding of the evolutionary mechanism of fused glass densification generation during single particle scratching

open access: yesJournal of Materials Research and Technology
The densification of fused glass during processing has a significant impact on the performance and application of fused glass components. However, the precise atomic mechanisms underlying densification remain elusive. In this study, we explore the atomic
Yueming Deng   +6 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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