Results 91 to 100 of about 7,192,600 (302)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The optimal substrate choice for effective biosensors based on THz metasurfaces

Scientific Reports
This article explores the impact of substrate choice on the sensitivity of sensors that utilize metallic terahertz metasurfaces as the actuating element.
Pradeep Tiwari, Deepak Kala, Maciej Sakowicz   +2 more
doaj   +1 more source

Pressure responses of halide perovskites with various compositions, dimensionalities, and morphologies

Matter and Radiation at Extremes, 2020
Metal halide perovskites (HPVs) have been greatly developed over the last decade, with various compositions, dimensionalities, and morphologies, leading to an emergence of high-performance photovoltaic and optoelectronic applications.
Mei Li, Tianbiao Liu, Yonggang Wang, Wenge Yang, Xujie Lü   +4 more
doaj   +1 more source

Ionic high-pressure form of elemental boron

, 2009
Boron is an element of fascinating chemical complexity. Controversies have shrouded this element since its discovery was announced in 1808: the new 'element' turned out to be a compound containing less than 60-70 percent of boron, and it was not until ...
A Masago, AF Wells, AR Oganov, Artem R. Oganov, B Edwards, BE Douglas, Carlo Gatti, Colin W. Glass, CW Glass, DN Sanz, E Amberger, G Kresse, G Will, H Werheit, IV Petryanov-Sokolov, Jiuhua Chen, JP Perdew, M Vlasse, MI Eremets, MI McMahon, MJ van Setten, Oleksandr O. Kurakevych, PE Blöchl, RFW Bader, S Baroni, Tony Yu, U Häussermann, VL Solozhenko, Vladimir L. Solozhenko, VV Brazhkin, W Hayami, X Gonze, Yanming Ma, Yanzhang Ma, YM Ma, YZ Ma, Zhenxian Liu   +36 more
core   +1 more source

High-Pressure Effects

, 2007
Chapter in Schrieffer's ...
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Band gap closure, incommensurability and molecular dissociation of dense chlorine

Nature Communications, 2019
Molecular systems are predicted to transform into atomic solids and be metallic at high pressure; this was observed for the diatomic elements iodine and bromine. Here the authors access the higher pressures needed to observe the dissociation in chlorine,
Philip Dalladay-Simpson, Jack Binns, Miriam Peña-Alvarez, Mary-Ellen Donnelly, Eran Greenberg, Vitali Prakapenka, Xiao-Jia Chen, Eugene Gregoryanz, Ross T. Howie   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Unveiling a novel metal-to-metal transition in LuH2: Critically challenging superconductivity claims in lutetium hydrides

Matter and Radiation at Extremes
Following the recent report by Dasenbrock-Gammon et al. [Nature 615, 244–250 (2023)] of near-ambient superconductivity in nitrogen-doped lutetium trihydride (LuH3−δNε), significant debate has emerged surrounding the composition and interpretation of the ...
Dong Wang, Ningning Wang, Caoshun Zhang, Chunsheng Xia, Weicheng Guo, Xia Yin, Kejun Bu, Takeshi Nakagawa, Jianbo Zhang, Federico Gorelli, Philip Dalladay-Simpson, Thomas Meier, Xujie Lü, Liling Sun, Jinguang Cheng, Qiaoshi Zeng, Yang Ding, Ho-kwang Mao   +17 more
doaj   +1 more source