Results 81 to 90 of about 18,903,450 (313)
Compressibility of insulin amyloid fibrils determined by X-ray diffraction in a diamond anvil cell
, 2009 Amyloid fibrils are fibrous structures that originate from the self-assembly of polypeptides. Their formation is linked to debilitating diseases associated with protein misfolding, including Alzheimer's disease and type-II diabetes.
Cabrera, Raul Quesada +5 more
core +1 more source
Scientific ReportsThree Machine Learning algorithms, namely Random Forest, Neural Networks and Extreme Gradient Boosting, were applied to recognize the shape and surface structure of diamond nanoparticles from powder diffraction data.
Kazimierz Skrobas +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
High‐Pressure Entry into Platencin
Angewandte Chemie, 2008 Contains fulltext : 72278.pdf (Publisher’s version ) (Open Access)
Waalboer, D.C.J. +3 more
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The optimal substrate choice for effective biosensors based on THz metasurfaces
Scientific ReportsThis article explores the impact of substrate choice on the sensitivity of sensors that utilize metallic terahertz metasurfaces as the actuating element.
Pradeep Tiwari +2 more
doaj +1 more source
CHRONOBIOLOGY OF HIGH BLOOD PRESSURE.
Scripta medica, 2007 BIOCOS, the project aimed at studying BIOlogical systems in their COSmos, has obtained a great deal of expertise in the fields of blood pressure (BP) and heart rate (HR) monitoring and of marker rhythmometry for the purposes of screening, diagnosis, treatment, and prognosis.
Cornélissen G +14 more
openaire +4 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Recent advances in synthesis, structure, and properties of binary and ternary transition metal phosphides [PDF]
Matter and Radiation at ExtremesTransition metal phosphides exhibit diverse crystal structures and intriguing physical properties, including superconductivity and magnetism. Despite extensive studies, obtaining a comprehensive understanding of the synthesis methods, structural ...
Xinyue Wang +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source