Results 71 to 80 of about 6,876,154 (338)

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

High-temperature, high-pressure spherical segment valve Patent [PDF]

, 1964
High-temperature, high-pressure spherical segment ...
Giovannetti, A., Jr., Himmelright, R. M., Meyer, K. A., Nitta, H.   +3 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

High impact pressure regulator Patent [PDF]

, 1969
High impact pressure regulator having minimum number of lightweight movable ...
Biles, J. E., Jr., Floyd, E. L., Topits, A., Jr.   +2 more
core   +1 more source

High-pressure melting curve of hydrogen [PDF]

, 2008
The melting curve of hydrogen was computed for pressures up to 200 GPa, using molecular dynamics. The inter- and intramolecular interactions were described by the reactive force field (ReaxFF) model.
Belonoshko, Anatoly B., Davis, Sergio M., Johansson, Börje, Skorodumova, Natalia V., van Duin, Adri C. T.   +4 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

High pressure air valve Patent [PDF]

, 1969
Development and characteristics of high pressure control ...
Howland, B. T.
core   +1 more source

Simple Metals at High Pressure

, 2009
In this lecture we review high-pressure phase transition sequences exhibited by simple elements, looking at the examples of the main group I, II, IV, V, and VI elements.
A Lazicki, A Ormeci, A Ormeci, A Phusittrakool, AM Teweldeberhan, C Hejny, C Hejny, CJ Pickard, D Errandonea, DA Young, DW Zhou, E Gregoryanz, E Gregoryanz, EG Maksimov, EYu. Tonkov, FJH Ehlers, G Gao, H Fujihisa, H Fujihisa, H Olijnyk, I Errea, I Loa, I Loa, J Sun, JB Neaton, JB Neaton, JM Perez-Mato, K Syassen, K Takemura, L Dubrovinsky, LF Lundegaard, LF Lundegaard, M Hanfland, M Hanfland, M Marqués, M Pravica, MI Katsnelson, MI McMahon, MI McMahon, MI McMahon, MI McMahon, MI McMahon, MI McMahon, MI McMahon, MI McMahon, MI McMahon, MI McMahon, NC Cunningham, NE Christensen, O Degtyareva, O Degtyareva, O Degtyareva, O Degtyareva, O Degtyareva, O Degtyareva, O Degtyareva, QF Gu, R Rousseau, RJ Nelmes, S Arapan, S Smaalen van, S Smaalen van, SK Reed, T Bovornratanaraks, T Ishikawa, T Ishikawa, T Ishikawa, T Kume, T Matsuoka, T Yabuuchi, U Häussermann, U Häussermann, U Schwartz, U Schwarz, U Schwarz, V Petrιcek, VF Degtyareva, VF Degtyareva, VF Degtyareva, VF Degtyareva, VV Struzhkin, WB Pearson, X Wang, Y Akahama, Y Akahama, Y Ma, Y Ma, Y Yao, Y Yao, YR Shen   +89 more
core   +1 more source

Melting of Iron Explored by Electrical Resistance Jump up to 135 GPa

Geophysical Research Letters, 2021
The melting temperature (Tm) of iron at megabar pressures constrains the Earth's core temperature structure and dynamics. Previous experimental studies demonstrated large discrepancies in Tm at high pressures.
Mingqiang Hou, Jin Liu, Youjun Zhang, Xueyan Du, Hongliang Dong, Limin Yan, Junyue Wang, Lin Wang, Bin Chen   +8 more
doaj   +1 more source