Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Visualized experimental study on the process of high-pressure gas jet impacting on liquid-water column [PDF]
To investigate the interaction laws governing the interaction between a gas jet and a liquid medium during the process of liquid-balanced launching, and to elucidate the influence of high-temperature gas on the characteristics of the gas–liquid ...
Jian Wang +3 more
doaj +1 more source
Determination of carbamazepine in serum and saliva samples by high performance liquid chromatography with ultraviolet detection [PDF]
Background/Aim. Carbamazepine is antiepileptic drug widely used for the treatment of epilepsy. Due to low therapeutic index of carbamazepine there is a need for routine measuring its concentrations in biological fluids.
Đorđević Snežana +2 more
doaj +1 more source
Quince Pomace: A Source of Fiber Products and Polyphenols
Quince fruits are used to make jams, jellies, and juices, resulting in by-products like seeds, pulp, and skin. These by-products contain bioactive compounds such as phenolic acids, flavonoids, and polysaccharides, which offer potential health benefits ...
Luminița Dimitriu +3 more
doaj +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
High Pressure Rheology of Lubricants (Part 5)
The Walther equation is often used for the viscosity temperature characteristics of lubricants. However, it was found that it cannot be applied to high pressure viscosity.
Masato Kaneko
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Medicago sativa (alfalfa) is a widely used animal feed. However, its quality has been difficult to control due to the lack of appropriate marker compounds.
Shixuan Zhang +4 more
doaj +1 more source

