Results 31 to 40 of about 17,657,684 (289)

Development of a High‐Pressure Reactor Based on Liquid‐Flow Pressurisation to Facilitate Enzymatic Hydroxylation of Gaseous Alkanes [PDF]

, 2019
A new type of high‐pressure reactor based on liquid‐flow pressurisation using a HPLC pump has been developed. This high‐pressure reactor allows the easy and safe performance of reactions with gaseous alkanes under high‐pressures up to 10 MPa (100 atm ...
Chie Kasai, Shinya Ariyasu, Shoji, Osami, Stanfield, Joshua Kyle, Joshua Kyle Stanfield, Yoshihito Watanabe, Kasai, Chie, Kodama, Yusaku, Zhiqi Cong, Osami Shoji, Aiba, Yuichiro, Ariyasu, Shinya, Watanabe, Yoshihito, Yusaku Kodama, Yuichiro Aiba, Cong, Zhiqi   +15 more
core   +1 more source

Hydroxymethylfurfural Content and Sugar Profile of Honey Available in Bangladesh Using Validated HPLC-PDA and HPLC-RID

Journal of Food Quality and Hazards Control, 2022
Background: Honey has a lot of reputation because of its supposed medicinal properties. In this study, Hydroxymethylfurfural (HMF), sugars, and Fructose/Glucose ratio of honey in Bangladesh were assessed for adulteration and authenticity evaluation ...
S. Das, M.N. Uddin, M.S. Haque, D. Chakraborty, M. Mostafa, A. Hasnaine, S.K. Das, M. Uddin   +7 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Determination of the Permeation and Penetration of Flurbiprofen into Cadaveric Human Pharynx Tissue

Clinical Pharmacology: Advances and Applications, 2020
Rob Turner,1 Sean Robert Wevrett,1 Suzanne Edmunds,1 Marc B Brown,1,2 Robert Atkinson,3 Oluwajoba Adegoke,3 Anuradha Kulasekaran,4 Tim Shea5 1MedPharm Ltd, Surrey Research Park, Guildford, UK; 2The Research Centre in Topical Drug Delivery and Toxicology (
Turner R, Wevrett SR, Edmunds S, Brown MB, Atkinson R, Adegoke O, Kulasekaran A, Shea T   +7 more
doaj  

Treatment with new organic nitrites in pulmonary hypertension of acute experimental pulmonary embolism

Pharmacology Research & Perspectives, 2019
Acute pulmonary embolism may cause right heart failure due to increased pulmonary vascular resistance and arterial hypoxemia. Effective vasodilator therapy of the pulmonary hypertension is highly needed.
Kristofer F. Nilsson, Lars E. Gustafsson
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Determination of carbamazepine in serum and saliva samples by high performance liquid chromatography with ultraviolet detection [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. Carbamazepine is antiepileptic drug widely used for the treatment of epilepsy. Due to low therapeutic index of carbamazepine there is a need for routine measuring its concentrations in biological fluids.
Đorđević Snežana, Kilibarda Vesna, Stojanović Tomislav   +2 more
doaj   +1 more source

Quince Pomace: A Source of Fiber Products and Polyphenols

Chemistry Proceedings, 2023
Quince fruits are used to make jams, jellies, and juices, resulting in by-products like seeds, pulp, and skin. These by-products contain bioactive compounds such as phenolic acids, flavonoids, and polysaccharides, which offer potential health benefits ...
Luminița Dimitriu, Daniel Preda, Diana Constantinescu-Aruxandei, Florin Oancea   +3 more
doaj   +1 more source