Results 241 to 250 of about 1,272,243 (389)

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos   +5 more
wiley   +1 more source

Development of Hydrofluoroolefin (HFO)‐based direct O‐fluoroalkenylation of phenols targeting tyrosine conjugation

open access: yesAdvanced Synthesis &Catalysis, Accepted Article.
Methodology for direct fluoroalkenylation of phenolic OH function was developed using a fluorinated electrophilic reagent derived from HFO1234ze gas. Besides various functionalized phenols, tyrosine and tyrosine‐based peptides were successfully conjugated under the optimized reaction conditions.
Rihárd Sisa   +2 more
wiley   +1 more source

Ammonia Dynamics in the Human Body: Insights in Biomedical Sensing Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Ammonia (NH3) is a significant biomarker in diagnostics, affecting the respiratory system, stomach, liver, kidneys, bladder, and gastrointestinal tract. NH3 detection, using sensors, has the potential to improve medical diagnosis. This review examines recent advancements in NH3 sensing technologies and explores future research directions, including ...
Annelot Nijkoops   +8 more
wiley   +1 more source

A 3D‐Printed Microfluidic Sensor Platform for Online Bioprocess Monitoring

open access: yesAdvanced Sensor Research, EarlyView.
A 3D‐printed microfluidic lab‐on‐a‐chip sensor platform is presented, compatible with various cultivation setups, that integrates sensors for pH, pO₂, pCO₂, glucose, lactate, and additionally features a sampling unit for small‐volume abstraction. With this platform, continuous real‐time monitoring of critical bioprocess parameters is enabled and ...
Christopher Heuer   +5 more
wiley   +1 more source

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