Results 61 to 70 of about 1,272,243 (389)
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Synthesis of hydrogen- and methyl-capped long-chain polyynes by intense ultrashort laser pulse irradiation of toluene [PDF]
Hydrogen- and methyl-capped polyynes were synthesized by irradiating pure liquid toluene with 35 femtosecond, 300 {\mu}J laser pulses having a central wavelength of 800 nm, generated by a regeneratively amplified Ti:sapphire tabletop laser at a repetition rate of 1 kHz.
arxiv +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Evaluation of homocysteine in blood bank donors [PDF]
Objective: To investigate the use of plasma homocysteine levelsin blood bank donors as a risk marker for the development ofcardiovascular diseases in healthy individuals.
Luiz Antonio Rosa
doaj
High-Pressure CO$_2$ Dissociation with Nanosecond Pulsed Discharges [PDF]
The efficiency of the conversion of CO$_2$ into CO with nanosecond repetitively pulsed discharges (NRP) is investigated in a high pressure batch reactor. Stable discharges are obtained at up to 12~bar. By-products of CO$_2$ splitting are measured with gas chromatography. The energy efficiency is determined for a range of processing times, pulse energy,
arxiv
Complete gradient-LC-ESI system on a chip for protein analysis [PDF]
This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed ...
Lee, T. D.+3 more
core
Glycan analysis of the chicken synaptic plasma membrane glycoproteins - a major synaptic N-glycan carries the LewisX determinant [PDF]
The majority of plasma membrane components are glycosylated. It is now widely accepted that this post-translational modification is crucial during the establishment, maintenance and function of the nervous system.
Koles, Kate+3 more
core +4 more sources
Laboratory protocols for producing thin‐film pH electrodes for sterilized single‐use technologies have been successfully developed into a semiautomated workflow, with higher throughput and precision of membrane thickness. Accuracies are within 0.05 pH units versus ground truth, and uncertainty analysis reveals the largest sources of error to be derived
Bingyuan Zhao+4 more
wiley +1 more source
Separation of the natural retinoids by high-pressure liquid chromatography
A reverse phase high-pressure liquid chromatography system for rapid separation of various retinoids (vitamin A and its analogs) with little or no degradation is described. This method permits detection of as little as 22 pmol of retinoic acid.
C A Frolik, T E Tavela, M B Sporn
doaj
Apple scab control with grapefruit seed extract: no alternative to chemical fungicides [PDF]
The growth inhibiting effect of four commercially available grapefruit seed extracts on the causal organism of apple scab Venturia inaequalis was tested.
Kelderer, Markus+5 more
core