Results 121 to 130 of about 193,097 (307)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The triggered behavior of a controlled corona stabilised cascade switch

, 2011
Corona stabilised switches have been shown to have advantages in pulse power switching applications due to their high repetition rates and low jitter.
Given, M, Lehr, J., Wilson, Mark, Wang, Tao, Lehr, Jane, Macgregor, Scott, Timoshkin, Igor   +6 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Enhanced resolution optoacoustic microscopy using a picosecond high repetition rate Q-switched microchip laser. [PDF]

J Biomed Opt, 2022
Nteroli G, Messa G, Dasa MK, Penttinen A, Härkönen A, Guina M, Podoleanu AG, Koutsikou S, Bradu A.   +8 more
europepmc   +1 more source

High-energy, kHz-repetition-rate, ps cryogenic Yb:YAG chirped-pulse amplifier

, 2010
We demonstrate amplification of picosecond laser pulses to 40 mJ at a 2 kHz pulse repetition frequency (PRF) from a two-stage cryogenic chirped-pulse Yb:YAG amplifier, composed of a regenerative amplifier (RGA) and a two-pass booster amplifier.
Shu-Wei Huang (170521), Aleem M Siddiqui (20190918), Juliet Gopinath (4377787), John D Hybl (20190921), Kyung-Han Hong (3959585), Tso Yee Fan (20190924), Franz X Kartner (20186238), Enbang Li (19587589), Darren Rand (20190915), Benjamin J Eggleton (16252154)   +9 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Gigahertz harmonic mode-locking with multi-watt sub-60-fs pulses in a Mamyshev oscillator

High Power Laser Science and Engineering
The Mamyshev oscillator (MO) is well-known for its high modulation depth, which provides an excellent platform for achieving both high average power and short pulse durations.
Feihong Qiao, Ze Li, Ning Jia, Xiangtong Zhai, Hao Liang, Zhiguo Lv   +5 more
doaj   +1 more source

High Repetition-Rate Lpp-Source Facility For Euvl

, 2007
In this work we present the status of our high repetition-rate/high power EUV source facility. The mass-limited target concept has demonstrated high conversion efficiencies (CE) previously, with precision solid state lasers. Currently, experiments are in
George, S. A., Bernath, R., Schmid, T., Cunado, J., Teerawattanasook, S.   +4 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Solution phase high repetition rate laser pump x-ray probe picosecond hard x-ray spectroscopy at the Stanford Synchrotron Radiation Lightsource. [PDF]

Struct Dyn, 2023
Reinhard M, Skoien D, Spies JA, Garcia-Esparza AT, Matson BD, Corbett J, Tian K, Safranek J, Granados E, Strader M, Gaffney KJ, Alonso-Mori R, Kroll T, Sokaras D.   +13 more
europepmc   +1 more source