Results 51 to 60 of about 20,980,761 (308)

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Any-Resolution Training for High-Resolution Image Synthesis

, 2022
ECCV 2022 camera ready version; project page https://chail.github.io/anyres-gan/
Lucy Chai, Michaël Gharbi, Eli Shechtman, Phillip Isola, Richard Zhang 0001   +4 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Efficient cation separation based on humidity control and adsorption

Nature Communications
Precise ion sieving techniques are of great importance in various fields including the energy and environment. However, existing extraction methods, often associated with environmental risks, are lack of selectivity, time-consuming, and high cost.
Jinjiang Liang, Xin Chen, Changming Li, Yining Zhang, Jiahao Feng, Chuxin Wu, Yunqing Yang, Ning Xue, Xinshui Zhang, Yihang Yang, Tianyi Gao, Ran Wei, Jiameng Yu, Xiangchen Hu, Yue Zhang, Yi Yu, Wei Liu   +16 more
doaj   +1 more source

Molten salt-assisted SiOx prelithiation for high-performance quasi-solid-state batteries

Nano Research
Silicon oxide (SiOx) anodes have emerged as a promising substitute for graphite anodes owing to their high specific capacity and cost-effectiveness.
Ran Wei, Luyao Wang, Jiameng Yu, Yining Zhang, Xiaoyan Wu, Yu Chen, Tianyi Gao, Xinshui Zhang, Yi Yu, Li Wang, Xiangming He, Wei Liu   +11 more
doaj   +1 more source

Synchronous quantitative analysis of chiral mesostructured inorganic crystals by 3D electron diffraction tomography

Nature Communications, 2022
Chiral mesostructured inorganic crystals exhibit distinctive twisting and helical hierarchical stacking. Here, the authors report a general approach for the synchronous quantitative analysis of rotation axis, torsion angle, pitch length, and arrangement ...
Jing Ai, Xueliang Zhang, Te Bai, Qing Shen, Peter Oleynikov, Yingying Duan, Osamu Terasaki, Shunai Che, Lu Han   +8 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Galaxies as High-resolution Telescopes [PDF]

The Astrophysical Journal, 2017
Abstract Recent observations show a population of active galaxies with milliarcsecond offsets between optical and radio emission. Such offsets can be an indication of extreme phenomena associated with supermassive black holes including relativistic jets, binary supermassive black holes, or even recoiling supermassive black holes ...
openaire   +3 more sources