Results 61 to 70 of about 2,671,831 (317)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

High resolution MRI of the brain at 4.7 Tesla using fast spin echo imaging

, 2003
Over recent years, high field MR scanners (3 T and above) have become increasingly widespread due to potential advantages such as higher signal-to-noise ratio.
Thomas, D.L., Roberts, S., Yousry, T.A., Ordidge, R.J., De Vita, E., Parkes, H.G., Kinchesh, P., Parkes, H., Shmueli, K., Yousry, T., Turner, R., Thomas, D., Ordidge, R.   +12 more
core   +1 more source

High-resolution optical and SAR image fusion for building database updating [PDF]

, 2011
This paper addresses the issue of cartographic database (DB) creation or updating using high-resolution synthetic aperture radar and optical images. In cartographic applications, objects of interest are mainly buildings and roads.
M. Spigai, V. Poulain, Spigai, Marc, Marthon, Philippe, J-Y Tourneret, P. Marthon, Tourneret, Jean-Yves, Poulain, Vincent, J. Inglada, Inglada, Jordi   +9 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Efficient cation separation based on humidity control and adsorption

Nature Communications
Precise ion sieving techniques are of great importance in various fields including the energy and environment. However, existing extraction methods, often associated with environmental risks, are lack of selectivity, time-consuming, and high cost.
Jinjiang Liang, Xin Chen, Changming Li, Yining Zhang, Jiahao Feng, Chuxin Wu, Yunqing Yang, Ning Xue, Xinshui Zhang, Yihang Yang, Tianyi Gao, Ran Wei, Jiameng Yu, Xiangchen Hu, Yue Zhang, Yi Yu, Wei Liu   +16 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Structural analysis of nanocrystals by pair distribution function combining electron diffraction with crystal tilting

IUCrJ
As an important characterization method, pair distribution function (PDF) has been extensively used in structural analysis of nanomaterials, providing key insights into the degree of crystallinity, atomic structure, local disorder etc.
Linshuo Guo, Shitao Wu, Zhengyang Zhou, Yanhang Ma   +3 more
doaj   +1 more source

Fast High Resolution Methods

, 1998
Publication in the conference proceedings of EUSIPCO, Rhodes, Greece ...
Frikel, M., Bourennane, Salah, Bendjama, A.   +2 more
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source