Results 101 to 110 of about 846,698 (293)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Characterizing dynamical processes in surface-bound exospheres via resolved sodium D emissions

open access: yesFrontiers in Astronomy and Space Sciences
Two techniques to quantify the energy of an atmospheric gas remotely are the emission scale height and linewidth spectroscopy at high spectral resolution.
Patrick Lierle   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

There’s More to Life in Reflected Light: Simulating the Detectability of a Range of Molecules for High-contrast, High-resolution Observations of Nontransiting Terrestrial Exoplanets

open access: yesThe Planetary Science Journal
The upcoming extremely large telescopes (ELTs) will provide the first opportunity to search for signs of habitability and life on nontransiting terrestrial exoplanets using high-contrast, high-resolution instrumentation. However, the suite of atmospheric
Miles H. Currie, Victoria S. Meadows
doaj   +1 more source

Unveiling the Variability and Chemical Composition of AL Col

open access: yesGalaxies
In this study, we present analysis of TESS photometry, spectral energy distribution (SED), high-resolution spectroscopy, and spot modeling of the α2 CVn-type star AL Col (HD 46462).
Surath C. Ghosh   +11 more
doaj   +1 more source

Intramolecular H-Bond Dynamics of Catechol Investigated by THz High-Resolution Spectroscopy of Its Low-Frequency Modes. [PDF]

open access: yesMolecules, 2021
Bruckhuisen J   +8 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Terahertz high-resolution spectroscopy of thermal decomposition gas products of diabetic and non-diabetic blood plasma and kidney tissue pellets. [PDF]

open access: yesJ Biomed Opt, 2021
Lykina AA   +8 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

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