Results 71 to 80 of about 2,092,528 (310)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Influence of an upstream building on the wind-induced mean suction on the flat roof of a low-rise building [PDF]

, 2011
The effect of an upstream building on the suction forces on the flat roof of a low-rise building placed in the wake of the former is analyzed. The analysis has been performed by wind tunnel testing of a flat roof, low-rise building model equipped with ...
Franchini, Sebastián, Meseguer Ruiz, José, Pindado Carrion, Santiago   +2 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

The impact of high-rise construction of urban buildings on the management of infrastructure, wastewater and urban waste with a construction management approach: Case example of Yasouj city [PDF]

مهندسی و مدیریت ساخت, 2023
The aim of the current research is the impact of high-rise urban buildings on the management of infrastructure, wastewater and urban waste with a construction management approach (case example of Yasouj city).
ali momeni manesh
doaj  

Buiding (High-Rise Building 1)

Wind Engineers, JAWE, 2001
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Cheng, C.-M., Lu, P.-C., Tsai, M.-S., Liang, Shuguo, Liu, Shengchun, Zhang, Liangliang, Gu, Ming, Young-Moon, Kim, Ki-Pou, You, Kawaguchi, Akihisa, Kanda, Makoto, Maruta, Eizo, Koizume, Tatuya, Tamura, Y., Matsui, M., Pagnini, Luisa-Carlotta, Ishibashi, R., Yoshida, A., Denoon, Roy O., Kwok, Kenny C. S., Roberts, Richard D.   +20 more
openaire   +3 more sources

Forced vibrations of high-rise buildings

IOP Conference Series: Materials Science and Engineering, 2020
Abstract Studies were conducted to analyze the behavior of a high-rise structure on various kinematic effects, taking into account the real geometry, dissipative and nonlinear properties of the structure material. A generalized approach was developed for the dynamic calculation of high-rise structures, and the frequency response ...
Sherzod Khudainazarov, Tulkin Mavlanov, Jakhongir Qosimov, Oliya Nurova   +3 more
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Fire safety engineering applied to high-rise building facades

MATEC Web of Conferences, 2016
Fire safety of high-rise building facades is a complex problem, therefore the use of prescriptive fire codes could not be sufficient to ensure a proper building fire safety level.
Sassi Samuele, Setti Paolo, Amaro Giuseppe, Mazziotti Lamberto, Paduano Giuseppe, Cancelliere Piergiacomo, Madeddu Mauro   +6 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Efficient three-dimensional modelling of high-rise building structures

Journal of Civil Engineering and Management, 2013
A multi-storey building is habitually modelled as a frame structure which neglects the shear wall/slab openings along with the inclusion of staircases. Furthermore, the structural strength provided by shear walls and slabs is not precisely incorporated ...
Mohammed Jameel, A. B. M. Saiful Islam, Mohammed Khaleel, Aslam Amirahmad   +3 more
doaj   +1 more source