Results 131 to 140 of about 4,939,655 (307)

Three-Dimensional Flutter Numerical Simulation of Wings in Heavy Gas and Transonic Flutter Similarity Law Correction Method

open access: yesAerospace
Wind tunnel testing is a crucial method for studying aircraft flutter. Using heavy gas as the wind tunnel medium can mitigate the escalating issue of test models being overweight as advanced aircraft develop.
Zhe Hu   +5 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Investigation on shakedown response-behavior of thawed subgrade soils under long-term traffic loading

open access: yesFrontiers in Earth Science
The shakedown state of the subgrade is crucial for the sustainable design and long-term stability evaluation of pavement structures. In order to characterize the plastic deformation and shakedown behavior of subgrade soil in seasonal frozen regions ...
Shujian Wang   +8 more
doaj   +1 more source

High speed transport cruise drag [PDF]

open access: yes
This report provides scaling laws for the cruise aerodynamics of high speed transport wings based on the results of Navier-Stokes computations. Expressions for the various drag components are found, together with the corresponding values (L/D)(sub m) for
Roberts, Leonard
core   +1 more source

Modelling High Speed Machining with the SPH Method [PDF]

open access: yes, 2008
The purpose of this work is to evaluate the use of the Smoothed Particle Hydrodynamics (SPH) method within the framework of high speed cutting modelling. First, a 2D SPH based model is carried out using the LS-DYNA® software.
Chieragatti, Rémy   +5 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subsonic and Transonic Mach Number Tracking Control Strategy Design and Application in an Intermittent Wind Tunnel

open access: yesIEEE Access
In order to ensure the quality of test data, the Mach number control deviation should be kept within a given range during the continuous-traverse mode force measurement test in a wind tunnel.
Liebo Ma   +3 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Effect of speed and load on ultra-high-speed ball bearings [PDF]

open access: yes
A study was undertaken to determine the effects of speed and load on the operation of 120-mm bore angular-contact ball bearings at speeds to 25,000 rpm and thrust loads to 22,240 newtons (5000 lb). Bearing temperature and power consumption increased with
Bamberger, E. N.   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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