Results 111 to 120 of about 4,970,035 (308)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

High speed multi focal plane optical system [PDF]

, 1983
An apparatus for eliminating beamsplitter generated optical aberrations in a pupil concentric optical system providing a plurality of spatially separated images on different focal planes or surfaces is presented.
Minott, P. O.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Electro-optic polymers for high speed modulators [PDF]

, 2005
Different electro-optic polymer systems are analyzed with respect to their electro-optic activity, glass transition temperature (Tg) and photodefinable properties. The polymers tested are polysulfone (PS) and polycarbonate (PC).
Balakrishnan, M, Diemeer, M.B.J., Driessen, A., Faccini, M., Leinse, A., Reinhoudt, D.N., Verboom, W.   +6 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

High Speed of Learning in Financial Markets [PDF]

, 2003
We analyze the role of liquidity and collection of information in order to measure the speed of revelation of information during the preopening of order-driven markets.
Germain, Laurent
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Data-driven capacity planning of highway multi-energy systems under photovoltaic uncertainty using CVAE-enhanced distributionally robust optimization

Frontiers in Energy Research
Capacity planning in highway multi-energy systems faces significant challenges due to the high uncertainty of renewable energy generation and the limited availability of historical data during the planning stage.
Guomu Xie, Guomu Xie, Xuefei Liu, Hongjie Li, Hongjie Li, Yuanyuan Song, Jikai Fu, Jikai Fu, Jibin Zhang, Jibin Zhang, Shishan Dong, Shishan Dong   +11 more
doaj   +1 more source

High speed sampling [PDF]

Mathematics of Computation, 1951
Votaw, D. F. jun., Rafferty, J. A.
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source