Results 111 to 120 of about 16,727,264 (297)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Florida High Speed Rail Authority - 2002 report to the legislature [PDF]

open access: yes
This report addresses a legislative requirement that the Authority issue a report of its actions, findings and recommendations. Previous high speed ground transportation studies were reviewed as part of the preparation of this report.
HNTB Corporation
core  

Simulation on Buffet Response and Mitigation of Variant-Tailed Aircraft in Maneuver State

open access: yesVibration
This study proposes a computational fluid dynamics and computational structure dynamics (CFD/CSD) coupled method for calculating the buffet response of a variant tail wing.
Dawei Liu   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Analysis of High Speed Local and Metropolitan Area Network

open access: yes, 2020
This thesis paper concentrates on high speed network technologies and techniques. The first contribution of this thesis is to give detailed information about high speed switch fabrics that are implementing in the high speed network and working principle ...
Aslanli, Orkhan
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Characteristics of a series of high speed hard chine planing hulls - part II: performance in waves

open access: yes, 2011
An experimental investigation into the performance of high speed hard chine planing hulls in irregular waves has been conducted. A new series of models representative of current design practice was developed and tested experimentally. Measurements of the
Taunton, D.J.   +2 more
core   +1 more source

Data-driven capacity planning of highway multi-energy systems under photovoltaic uncertainty using CVAE-enhanced distributionally robust optimization

open access: yesFrontiers in Energy Research
Capacity planning in highway multi-energy systems faces significant challenges due to the high uncertainty of renewable energy generation and the limited availability of historical data during the planning stage.
Guomu Xie   +11 more
doaj   +1 more source

High speed sampling [PDF]

open access: yesMathematics of Computation, 1951
Votaw, D. F. jun., Rafferty, J. A.
openaire   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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