Results 91 to 100 of about 4,970,035 (308)

Investigation on the rolling contact fatigue cracks initiation of subway fixed frogs based on transient dynamics

open access: yesRailway Engineering Science
The issue of fatigue damage to rails has become increasingly prominent with the rise in subway traffic and speed. The hazardous space of the turnout frog significantly intensifies the dynamic interaction between the vehicle and the frog rail, leading to ...
Zhaoguang Zheng   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Distributed associative memories for high-speed symbolic reasoning [PDF]

open access: yes, 1996
This paper briefly introduces a novel symbolic reasoning system based upon distributed associative memories which are constructed from correlation matrix memories (CMM). The system is aimed at high-speed rule-based symbolic operations.
Austin, J
core   +1 more source

Reynolds Number Effect of a Supercritical Wing Based on Cryogenic and High Reynolds Number Pressure Test

open access: yesAerospace
Supercritical wings are widely used in large aircraft due to their excellent transonic performance, but their aerodynamic characteristics are highly sensitive to Reynolds number. To systematically study the influence of Reynolds number on the aerodynamic
Baobin Hou   +5 more
doaj   +1 more source

High speed interferometric ellipsometer

open access: yesOptics Express, 2008
A novel high speed interferometric ellipsometer (HSIE) is proposed and demonstrated. It is based on a novel differential-phase decoder which is able to convert the phase modulation into amplitude modulation in a polarized heterodyne interferometer.
Tsai, C. C.   +5 more
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Flexible high speed codec [PDF]

open access: yes
The project's objective is to develop an advanced high speed coding technology that provides substantial coding gains with limited bandwidth expansion for several common modulation types.
Boyd, R. W., Hartman, W. F.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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