Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Rotor integrity design for a high-speed modular air-cored axial-flux permanent-magnet generator [PDF]
The rotor integrity design for a high-speed modular air-cored axial-flux permanent-magnet (AFPM) generator is presented. The main focus is on the mechanical parametric optimization of the rotor, which becomes a more dominating design issue over ...
Luk, Patrick Chi-Kwong +5 more
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Combined use of High-Speed Videography and PDV Profilometry for Measuring High Speeds Flyers and Impact Shock Dynamics [PDF]
Challenges remain in understanding the dynamic forces that occur with small scale explosive detonations and the subsequent impact those forces have on flyer velocity and deformation profiles.
Thurston, B. +5 more
core +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Estimation of railway vehicle speed using ground vibration measurements [PDF]
In railway noise and vibration assessment, the vehicle speed is a significant concern, since vehicle/track and track/soil interaction strongly affects the vibration magnitude.
Verlinden, Olivier +4 more
core
High-Speed Smart Camera with High Resolution
High-speed video cameras are powerful tools for investigating for instance the biomechanics analysis or the movements of mechanical parts in manufacturing processes. In the past years, the use of CMOS sensors instead of CCDs has enabled the development of high-speed video cameras offering digital outputs, readout flexibility, and lower manufacturing ...
Romuald Mosqueron +2 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Research on High Speed Aerodynamics at the Royal Aircraft Establishment from 1942 to 1945 [PDF]
Summary.-A brief description of the Royal Aircraft Establishment (R.A.E.) High Speed Wind Tunnel is given, together with an account of the methods used for calibrating the tunnel and for testing models in it.
The Staffs Of The High Speed Tunnel And High Speed Flight Sections
core
Feed rate modeling in circular–circular interpolation discontinuity for high-speed milling [PDF]
In this paper, a modeling approach is presented in order to evaluate feed rate during a circular interpolation in high-speed milling. The developed model depends on the type of discontinuity and the kinematic performance of the machine tool.
Baili, Maher +4 more
core +1 more source

