Results 61 to 70 of about 4,939,655 (307)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
High speed, self-acting shaft seal [PDF]
A high-speed, self-acting circumferential type shaft seal for use in turbine engines is disclosed. One or more conventional circumferential ring seals having a central aperture are mounted in a housing.
Hady, W. F., Ludwig, L. P.
core +1 more source
High Speed Photometry of SDSS J013701.06-091234.9 [PDF]
We present high speed photometry of the Sloan Digital Sky Survey cataclysmic variable SDSS J013701.06-091234.9 in quiescence and during its 2003 December superoutburst.
Araujo-Betancor +33 more
core +3 more sources
Integrazione tra le discipline che studiano le trasformazioni urbane e quelle che affrontano le tematiche del governo della mobilità per la costruzione di un nuovo corpus di conoscenze teorico-metodologiche che, superando gli steccati che segnano il confine – del tutto apparente – tra queste discipline, sia in grado di formulare soluzioni nuove ai ...
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Shaft seal assembly for high speed and high pressure applications [PDF]
A seal assembly is provided for reducing the escape of fluids from between a housing and a shaft rotably mounted in the housing. The seal assembly comprises a pair of seal rings resiliently connected to each other and disposed in side-by-side ...
Hadt, W. F., Ludwig, L. P.
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
High-speed Civil Transport Aircraft Emissions [PDF]
Estimates are given for the emissions from a proposed high speed civil transport (HSCT). This advanced technology supersonic aircraft would fly in the lower stratosphere at a speed of roughly Mach 1.6 to 3.2 (470 to 950 m/sec or 920 to 1850 knots ...
Albers, Martin +9 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
SPH method applied to high speed cutting modelling [PDF]
The purpose of this study is to introduce a new approach of high speed cutting numerical modelling. A Lagrangian smoothed particle hydrodynamics (SPH)- based model is arried out using the Ls-Dyna software.
Chieragatti, Rémy +4 more
core +3 more sources

